Bovine viral diarrhoea virus in beef heifers in commercial herds in Australia: Mob-level seroprevalences and incidences of seroconversion, and vaccine efficacy

Morton, J. M., Phillips, N. J., Taylor, L. F. and Mcgowan, M. R. (2013) Bovine viral diarrhoea virus in beef heifers in commercial herds in Australia: Mob-level seroprevalences and incidences of seroconversion, and vaccine efficacy. Australian Veterinary Journal, 91 12: 517-524. doi:10.1111/avj.12129


Author Morton, J. M.
Phillips, N. J.
Taylor, L. F.
Mcgowan, M. R.
Title Bovine viral diarrhoea virus in beef heifers in commercial herds in Australia: Mob-level seroprevalences and incidences of seroconversion, and vaccine efficacy
Journal name Australian Veterinary Journal   Check publisher's open access policy
ISSN 0005-0423
1751-0813
Publication date 2013-01-01
Year available 2013
Sub-type Article (original research)
DOI 10.1111/avj.12129
Volume 91
Issue 12
Start page 517
End page 524
Total pages 8
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing Ltd.
Language eng
Subject 3400 Veterinary
Abstract Objectives: To describe management group (mob)-level seroprevalences and incidences of seroconversion to bovine viral diarrhoea virus (BVDV), and to determine the efficacy of a vaccine against BVDV, in beef heifers in commercial herds in Australia. Methods: Seroprevalences were assessed in 38 mobs of beef heifers. Of them, 15 mobs that were considered to be at higher risk of BVDV transmission during the upcoming mating period underwent further serological monitoring, and were included in a double-blind controlled trial to assess vaccine efficacy. Results: In 66% of mobs, less than half the heifers were seropositive some months before mating start date. However, in only 2 mobs was the incidence of seroconversion during the mating period greater than 10%, with a very high incidence of seroconversion observed in only 1 mob. The pregnancy proportion in placebo-treated heifers in this mob was acceptable (89%), but a high proportion of placebo-treated heifers (26%) had persistently infected calves. The efficacy of the Pestigard® vaccine in preventing the birth of infected calves was estimated as 80%. Conclusions: Outbreaks of serious BVDV-related disease are relatively uncommon in mobs of beef heifers, but when they occur, the impact can be large. This highlights the need to approach BVDV control from a risk-assessment perspective, where the likelihood and consequences of widespread BVDV infection in a mob are jointly assessed. Pestigard® vaccination of naïve heifers prior to mating reduces the risk of transplacental infection with BVDV if heifers are exposed to BVDV during early pregnancy.
Keyword Incidence
Seroprevalence
Vaccination
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Veterinary Science Publications
 
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