Nanoparticles mimicking viral surface topography for enhanced cellular delivery

Niu, Yuting, Yu, Meihua, Hartono, Sandy B., Yang, Jie, Xu, Hongyi, Zhang, Hongwei, Zou, Jun, Zou, Jin, Dexter, Annette, Gu, Wenyi and Yu, Chengzhong (2013) Nanoparticles mimicking viral surface topography for enhanced cellular delivery. Advanced Materials, 25 43: 6233-6237. doi:10.1002/adma.201302737


Author Niu, Yuting
Yu, Meihua
Hartono, Sandy B.
Yang, Jie
Xu, Hongyi
Zhang, Hongwei
Zou, Jun
Zou, Jin
Dexter, Annette
Gu, Wenyi
Yu, Chengzhong
Title Nanoparticles mimicking viral surface topography for enhanced cellular delivery
Journal name Advanced Materials   Check publisher's open access policy
ISSN 0935-9648
1521-4095
Publication date 2013-11-20
Year available 2013
Sub-type Article (original research)
DOI 10.1002/adma.201302737
Open Access Status Not yet assessed
Volume 25
Issue 43
Start page 6233
End page 6237
Total pages 5
Place of publication Weinheim, Germany
Publisher Wiley - V C H Verlag GmbH & Co. KGaA
Language eng
Abstract Novel silica nanoparticles mimicking virus surface topography are prepared. It is demonstrated that increases in nanoscale surface roughness promote both binding of biomolecules and cellular uptake; thus, the cellular delivery efficiency is significantly increased (scale bars 20â€...μm).
Keyword Biomimetic synthesis
Drug delivery
Nanoparticles
Surface topography
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Tue, 03 Dec 2013, 10:33:52 EST by System User on behalf of Aust Institute for Bioengineering & Nanotechnology