Effects of self-reported osteoarthritis on physical performance: A longitudinal study with a 10-year follow-up

Van Leeuwen, Daniel M., Peeters, Geeske M. E. E., De Ruiter, Cornelis J., Lips, Paul, Twisk, Jos W. R., Deeg, Dorly J. H. and De Haan, Arnold (2013) Effects of self-reported osteoarthritis on physical performance: A longitudinal study with a 10-year follow-up. Aging - Clinical and Experimental Research, 25 5: 561-569. doi:10.1007/s40520-013-0110-1

Author Van Leeuwen, Daniel M.
Peeters, Geeske M. E. E.
De Ruiter, Cornelis J.
Lips, Paul
Twisk, Jos W. R.
Deeg, Dorly J. H.
De Haan, Arnold
Title Effects of self-reported osteoarthritis on physical performance: A longitudinal study with a 10-year follow-up
Journal name Aging - Clinical and Experimental Research   Check publisher's open access policy
ISSN 1594-0667
Publication date 2013-01-01
Year available 2013
Sub-type Article (original research)
DOI 10.1007/s40520-013-0110-1
Volume 25
Issue 5
Start page 561
End page 569
Total pages 9
Place of publication Heidelberg, Germany
Publisher Springer
Language eng
Subject 1302 Curriculum and Pedagogy
2717 Geriatrics and Gerontology
Abstract Background and aims: Osteoarthritis (OA) of the knee or hip is associated with limitations in activities of daily life. There are only a few long-term studies on how knee or hip OA affects the course of physical performance. The aim of this study was to investigate the effects of knee or hip OA on physical performance during a follow-up period of 10 years. Methods: Participants in the Longitudinal Aging Study Amsterdam with self-reported hip or knee OA (N = 155) were prospectively followed for 10 years on 4 occasions from the onset of OA and compared to participants without OA (N = 1004). Physical performance was tested with walk, chair stand and balance tests. Scores for each test were summed to a total performance score (range 0-12), higher scores indicating better performance. Generalized estimating equations were used to analyze differences between participants with and without OA, unadjusted as well as adjusted for confounders. Results: There was a significant interaction between OA and sex (P = 0.068). Both in men and women, total performance was lower for participants with OA, with greater differences in men. Chair stand and walking performance (P < 0.05), but not balance, were lower in participants with OA. After adjustment for confounders, these associations remained significant in men but not in women. Additional analyses correcting for follow-up duration and attrition showed lower performance scores for men and women with OA. Conclusions: OA negatively affected physical performance 3-6 years after it was first reported. Performance in men with OA was more affected than in women.
Keyword Osteoarthritis
Physical functioning
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Human Movement and Nutrition Sciences Publications
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