Topics in research: Structuring studies in palliative care

Davis, Mellar P. and Mitchell, Geoffrey K. (2012) Topics in research: Structuring studies in palliative care. Current Opinion in Supportive and Palliative Care, 6 4: 483-489. doi:10.1097/SPC.0b013e32835843d7


Author Davis, Mellar P.
Mitchell, Geoffrey K.
Title Topics in research: Structuring studies in palliative care
Journal name Current Opinion in Supportive and Palliative Care   Check publisher's open access policy
ISSN 1751-4258
1751-4266
Publication date 2012-01-01
Year available 2012
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/SPC.0b013e32835843d7
Open Access Status Not Open Access
Volume 6
Issue 4
Start page 483
End page 489
Total pages 7
Place of publication London, United Kingdom
Publisher Lippincott Williams and Wilkins, Ltd.
Language eng
Subject 2730 Oncology
2700 Medicine
2706 Critical Care and Intensive Care Medicine
2917 Oncology (nursing)
Abstract Purpose of review This review describes the advances in trial methodology and presents new methodologies to meet some of the challenges of conducting trials in a palliative care setting. To describe why this review is timely and relevant. Recent findings This review discusses the process required to conduct trials of complex interventions described by the Britain's Medical Research Council. It discusses the importance of feasibility trials and the quantitative research inherent in these trials. It describes the design alternatives to the classic randomized controlled trials (RCTs), including cluster randomization, step wedge and fast-track randomization, and n-of-1 trial design. The strengths and weaknesses of each are described. Summary An understanding of the limitations of RCTs is important. It is important that clinicians and researchers understand the need for alternative trial design and how and when to use them.
Keyword Complex interventions
Formal feasibility trials
Randomization
Research
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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