An antioxidant link between sickle cell disease and severe malaria

Haque, Ashraful and Engwerda, Christian R. (2011) An antioxidant link between sickle cell disease and severe malaria. Cell, 145 3: 335-336. doi:10.1016/j.cell.2011.04.004


Author Haque, Ashraful
Engwerda, Christian R.
Title An antioxidant link between sickle cell disease and severe malaria
Journal name Cell   Check publisher's open access policy
ISSN 0092-8674
1097-4172
Publication date 2011-04-29
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.cell.2011.04.004
Open Access Status Not Open Access
Volume 145
Issue 3
Start page 335
End page 336
Total pages 2
Place of publication Cambridge, MA, United States
Publisher Cell Press
Language eng
Abstract Although a link between sickle cell disease and resistance to severe malaria is well established, the biochemical relationship between the two is unknown. Ferreira et al. (2011) show that carriers of the sickle cell mutation increase expression of the heme oxygenase-1 enzyme, which produces antioxidant molecules that may prevent severe disease symptoms.
Keyword Biochemistry & Molecular Biology
Cell Biology
Biochemistry & Molecular Biology
Cell Biology
BIOCHEMISTRY & MOLECULAR BIOLOGY
CELL BIOLOGY
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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