Chapter 11 Genome Sequencing and Assembly

McGrath A. (2007) Chapter 11 Genome Sequencing and Assembly. Perspectives in Bioanalysis, 2 327-355. doi:10.1016/S1871-0069(06)02011-8


Author McGrath A.
Title Chapter 11 Genome Sequencing and Assembly
Journal name Perspectives in Bioanalysis
ISSN 1871-0069
ISBN 9780444522238
Publication date 2007-01-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/S1871-0069(06)02011-8
Volume 2
Start page 327
End page 355
Total pages 29
Subject 1300 Biochemistry, Genetics and Molecular Biology
1602 Criminology
1603 Demography
1606 Political Science
Abstract From the advent of genome sequencing and assembly in to the 1970s to the present day a great deal has been achieved in genome science. We now have the experimental means, tools and computing hardware necessary to successfully sequence and assemble large complex genomes. However challenges remain and draft genome sequences are widely known to contain misassemblies, largely due to repetitive DNA. As technology advances, new ways to generate large amounts sequence data in a short time and the increasing use of low-coverage genome scans are resulting in a greater reliance on bioinformatics tools for sequence assembly and comparison. With these new directions in genome science, this research area will remain as an active one for some time.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Scopus Import - Archived
 
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