"Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses

Colson, Philippe, De Lamallerie, Xavier, Yutin, Natalya, Asgari, Sassan, Bigot, Yves, Bideshi, Dennis K., Cheng, Xiao-Wen, Federici, Brian A., Van Etten, James L., Koonin, Eugene V., La Scola, Bernard and Raoult, Didier (2013) "Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. Archives of Virology, 158 12: 2517-2521. doi:10.1007/s00705-013-1768-6

Author Colson, Philippe
De Lamallerie, Xavier
Yutin, Natalya
Asgari, Sassan
Bigot, Yves
Bideshi, Dennis K.
Cheng, Xiao-Wen
Federici, Brian A.
Van Etten, James L.
Koonin, Eugene V.
La Scola, Bernard
Raoult, Didier
Title "Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses
Journal name Archives of Virology   Check publisher's open access policy
ISSN 0304-8608
Publication date 2013-06-29
Sub-type Article (original research)
DOI 10.1007/s00705-013-1768-6
Open Access Status Not yet assessed
Volume 158
Issue 12
Start page 2517
End page 2521
Total pages 5
Place of publication Vienna, Austria
Publisher Springer
Language eng
Formatted abstract
The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae". The family Mimiviridae includes the largest known viruses, with genomes in excess of one megabase, whereas the genome size in the other NCLDV families varies from 100 to 400 kilobase pairs. Most of the NCLDVs replicate in the cytoplasm of infected cells, within so-called virus factories. The NCLDVs share a common ancient origin, as demonstrated by evolutionary reconstructions that trace approximately 50 genes encoding key proteins involved in viral replication and virion formation to the last common ancestor of all these viruses. Taken together, these characteristics lead us to propose assigning an official taxonomic rank to the NCLDVs as the order "Megavirales", in reference to the large size of the virions and genomes of these viruses.
Keyword Megavirales
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Biological Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 107 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 21 Nov 2013, 21:13:34 EST by Prof Sassan Asgari on behalf of School of Biological Sciences