Recent developments in functional and structural imaging of aphasia recovery after stroke

Meinzer, Marcus, Harnish, Stacy, Conway, Tim and Crosson, Bruce (2011) Recent developments in functional and structural imaging of aphasia recovery after stroke. Aphasiology, 25 3: 271-290. doi:10.1080/02687038.2010.530672

Author Meinzer, Marcus
Harnish, Stacy
Conway, Tim
Crosson, Bruce
Title Recent developments in functional and structural imaging of aphasia recovery after stroke
Journal name Aphasiology   Check publisher's open access policy
ISSN 0268-7038
Publication date 2011-01-01
Year available 2011
Sub-type Article (original research)
DOI 10.1080/02687038.2010.530672
Open Access Status Not yet assessed
Volume 25
Issue 3
Start page 271
End page 290
Total pages 20
Place of publication Abingdon, Oxon, United Kingdom
Publisher Routledge
Language eng
Formatted abstract
Background: Functional and structural neuroimaging techniques can increase our knowledge about the neural processes underlying recovery from post-stroke language impairments (aphasia).

Aims: In the present review we highlight recent developments in neuroimaging research of aphasia recovery.

Main Contribution: We review (a) cross-sectional findings in aphasia with regard to local brain functions and functional connectivity, (b) structural and functional imaging findings using longitudinal (intervention) paradigms, (c) new adjunct treatments that are guided by functional imaging techniques (e.g., electrical brain stimulation) and (d) studies related to the prognosis of language recovery and treatment responsiveness after stroke.

Conclusions: More recent developments in data acquisition and analysis foster better understanding and more realistic modelling of the neural substrates of language recovery after stroke. Moreover, the combination of different neuroimaging protocols can provide converging evidence for neuroplastic brain remodelling during spontaneous and treatment-induced recovery. Researchers are also beginning to use sophisticated imaging analyses to improve accuracy of prognosis, which may eventually improve patient care by allowing for more efficient treatment planning. Brain stimulation techniques offer a new and exciting way to improve the recovery potential after stroke.
Keyword Aphasia
Functional imaging
Structural imaging
Brain stimulation
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID 01EO0801
R01 DC007387
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
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