Research review: epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010

Erskine, Holly E., Ferrari, Alize J., Nelson, Paul, Polanczyk, Guilherme V., Flaxman, Abraham D., Vos, Theo, Whiteford, Harvey A. and Scott, James G. (2013) Research review: epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010. Journal of Child Psychology and Psychiatry and Allied Disciplines, 54 12: 1263-1274. doi:10.1111/jcpp.12144

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads

Author Erskine, Holly E.
Ferrari, Alize J.
Nelson, Paul
Polanczyk, Guilherme V.
Flaxman, Abraham D.
Vos, Theo
Whiteford, Harvey A.
Scott, James G.
Title Research review: epidemiological modelling of attention-deficit/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010
Journal name Journal of Child Psychology and Psychiatry and Allied Disciplines   Check publisher's open access policy
ISSN 0021-9630
1469-7610
Publication date 2013-12-01
Year available 2013
Sub-type Article (original research)
DOI 10.1111/jcpp.12144
Open Access Status Not yet assessed
Volume 54
Issue 12
Start page 1263
End page 1274
Total pages 12
Place of publication Malden, MA, United States
Publisher Wiley-Blackwell Publishing
Language eng
Abstract BackgroundThe most recent Global Burden of Disease Study (GBD 2010) is the first to include attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) for burden quantification. We present the epidemiological profiles of ADHD and CD across three time periods for 21 world regions.
Formatted abstract
Background The most recent Global Burden of Disease Study (GBD 2010) is the first to include attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) for burden quantification. We present the epidemiological profiles of ADHD and CD across three time periods for 21 world regions.

Methods A systematic review of global epidemiology was conducted for each disorder (based on a literature search of the Medline, PsycInfo and EMBASE databases). A Bayesian metaregression tool was used to derive prevalence estimates by age and sex in three time periods (1990, 2005 and 2010) for 21 world regions including those with little or no data. Prior expert knowledge and covariates were applied to each model to adjust suboptimal data. Final prevalence output for ADHD were adjusted to reflect an equivalent value if studies had measured point prevalence using multiple informants while final prevalence output for CD were adjusted to reflect a value equivalent to CD only.

Results Prevalence was pooled for males and females aged 5–19 years with no difference found in global prevalence between the three time periods. Male prevalence of ADHD in 2010 was 2.2% (2.0–2.3) while female prevalence was 0.7% (0.6–0.7). Male prevalence of CD in 2010 was 3.6% (3.3–4.0) while female prevalence was 1.5% (1.4–1.7). ADHD and CD were estimated to be present worldwide with ADHD prevalence showing some regional variation while CD prevalence remained relatively consistent worldwide.

Conclusions We present the first prevalence estimates of both ADHD and CD globally and for all world regions. Data were sparse with large parts of the world having no estimates of either disorder. Epidemiological studies are urgently needed in certain parts of the world. Our findings directly informed burden quantification for GBD 2010. As mental disorders gained increased recognition after the first GBD study in 1990, the inclusion of ADHD and CD in GBD 2010 ensures their importance will be recognized alongside other childhood disorders.
Keyword Global burden of disease study 2010
Attention-deficit/hyperactivity disorder
Conduct disorder
Prevalence
Statistical modelling
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 48 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 54 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 18 Oct 2013, 19:21:13 EST by James Scott on behalf of School of Public Health