Enteroviral myocarditis in neonates

Schlapbach, Luregn J., Ersch, Joerg, Balmer, Christian, Pretre, Rene, Tomaske, Maren, Caduff, Rosmarie, Morwood, Jim, Provenzano, Sylvio and Stocker, Christian (2013) Enteroviral myocarditis in neonates. Journal of Paediatrics and Child Health, 49 9: E451-E454. doi:10.1111/jpc.12248

Author Schlapbach, Luregn J.
Ersch, Joerg
Balmer, Christian
Pretre, Rene
Tomaske, Maren
Caduff, Rosmarie
Morwood, Jim
Provenzano, Sylvio
Stocker, Christian
Title Enteroviral myocarditis in neonates
Journal name Journal of Paediatrics and Child Health   Check publisher's open access policy
ISSN 1034-4810
Publication date 2013-09-01
Year available 2013
Sub-type Article (original research)
DOI 10.1111/jpc.12248
Open Access Status Not yet assessed
Volume 49
Issue 9
Start page E451
End page E454
Total pages 4
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell
Language eng
Abstract Enteroviruses are a leading cause of viral infections in children. While most enteroviral infections are mild and self-limiting, severe disease such as a viral sepsis syndrome, myocarditis, hepatitis and meningoencephalitis may occur. We present two cases of neonatal enteroviral myocarditis. Cardiorespiratory failure occurred in both cases, and severe shock refractory to conventional treatment required support with extracorporeal membrane oxygenation (ECMO). One child with coxsackievirus B3 myocarditis failed to recover and died after 3 weeks on ECMO, while one child could be decannulated successfully after 9 days of ECMO and recovered completely subsequently. In conclusion, neonatal myocarditis has a very high mortality, and ECMO should be considered early in neonates with rapid clinical and echocardiographic deterioration despite adequate inotropic support.
Keyword Coxsackievirus
Extracorporeal membrane oxygenation
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Case report.

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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