The inflammatory conundrum - where exactly do we stand?

Lipman, J. and Piccolo, R. (1998) The inflammatory conundrum - where exactly do we stand?. South African Medical Journal, 88 11: 1441-1442. doi:10.1186/s13071-016-1799-4


Author Lipman, J.
Piccolo, R.
Title The inflammatory conundrum - where exactly do we stand?
Journal name South African Medical Journal   Check publisher's open access policy
ISSN 0038-2469
0256-9574
Publication date 1998-11-01
Year available 1998
Sub-type Editorial
DOI 10.1186/s13071-016-1799-4
Open Access Status Not Open Access
Volume 88
Issue 11
Start page 1441
End page 1442
Total pages 2
Place of publication Claremont, South Africa
Publisher Health and Medical Publishing Group
Language eng
Abstract Schistosomiasis, caused mainly by S. mansoni, S. haematobium and S. japonicum, continues to be a serious tropical disease and public health problem resulting in an unacceptably high level of morbidity in countries where it is endemic. Praziquantel, the only drug currently available for treatment, is unable to kill developing schistosomes, it does not prevent re-infection and its continued extensive use may result in the future emergence of drug-resistant parasites. This scenario provides impetus for the development and deployment of anti-schistosome vaccines to be used as part of an integrated approach for the prevention, control and eventual elimination of schistosomiasis. This review considers the present status of candidate vaccines for schistosomiasis, and provides some insight on future vaccine discovery and design.
Keyword Permeability-increasing protein
Septic shock
Nitric-oxide
Binding
Sepsis
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Editorial
Collection: Faculty of Health and Behavioural Sciences -- Publications
 
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