More vasomotor symptoms in menopause among women with a history of hypertensive pregnancy diseases compared with women with normotensive pregnancies

Drost, Jose T., van der Schouw, Yvonne T, Herber-Gast, Gerrie-Cor M and Maas, Angela HEM (2013) More vasomotor symptoms in menopause among women with a history of hypertensive pregnancy diseases compared with women with normotensive pregnancies. Menopause, 20 10: 1006-1011. doi:10.1097/GME.0b013e3182886093


Author Drost, Jose T.
van der Schouw, Yvonne T
Herber-Gast, Gerrie-Cor M
Maas, Angela HEM
Title More vasomotor symptoms in menopause among women with a history of hypertensive pregnancy diseases compared with women with normotensive pregnancies
Journal name Menopause   Check publisher's open access policy
ISSN 1072-3714
1530-0374
Publication date 2013-10-01
Year available 2013
Sub-type Article (original research)
DOI 10.1097/GME.0b013e3182886093
Volume 20
Issue 10
Start page 1006
End page 1011
Total pages 6
Place of publication Philadelphia, PA United States
Publisher Lippincott Williams and Wilkins
Language eng
Formatted abstract
OBJECTIVE: Cardiovascular disease is the major cause of mortality in women worldwide. In recent years, several female-specific cardiovascular risk factors, such as hypertensive pregnancy diseases (HPDs) and vasomotor menopausal symptoms (VMS), have been identified. In this study, we evaluated the association between a history of HPD and the presence of VMS.

METHODS:
We consecutively included 853 women (mean age, 55.5 y) who visited the outpatient cardiovascular clinic for women in Kampen between 2003 and 2010. The visit included a questionnaire on history of HPD, demographic characteristics, and VMS; physical examination; and blood sampling. Logistic regression analysis was used to analyze the data.

RESULTS: A history of HPD was reported by 274 women (32%), and VMS were reported by 83% of women with a history of HPD and by 75% of women without a history of HPD. In adjusted models, VMS were more often present (odds ratio [OR], 1.62; 95% CI, 1.00-2.63) and more frequently persisted for longer than 1 year (OR, 2.05; 95% CI, 1.08-3.89) among women with a history of HPD than among women with normotensive pregnancies. VMS were more often severe in women with a history of HPD, but this did not reach significance (adjusted OR, 1.28; 95% CI, 0.92-1.80). The frequency and intensity of VMS did not differ between both groups.

CONCLUSIONS:
In our "Kampen women cardiology clinic" cohort, women with a history of HPD report VMS during the menopausal transition significantly more often than women with normotensive pregnancies.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Public Health Publications
 
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Created: Tue, 23 Jul 2013, 22:16:31 EST by Gerrie-Cor Herber-Gast on behalf of School of Public Health