Neonatal neutropenia associated with maternal hypertension poses a risk for nosocomial infection

Gray, PH and Rodwell, RL (1999) Neonatal neutropenia associated with maternal hypertension poses a risk for nosocomial infection. European Journal of Pediatrics, 158 1: 71-73. doi:10.1007/s004310051013


Author Gray, PH
Rodwell, RL
Title Neonatal neutropenia associated with maternal hypertension poses a risk for nosocomial infection
Journal name European Journal of Pediatrics   Check publisher's open access policy
ISSN 0340-6199
Publication date 1999-01-01
Year available 1996
Sub-type Article (original research)
DOI 10.1007/s004310051013
Open Access Status Not yet assessed
Volume 158
Issue 1
Start page 71
End page 73
Total pages 3
Place of publication NEW YORK
Publisher BLACKWELL SCIENCE
Language eng
Abstract One hundred and six neonates of 24-32 weeks gestation born to hypertensive mothers and 106 concurrent control infants of normotensive mothers were evaluated to determine the relationship between maternal hypertension and neonatal neutropenia and the risk of nosocomial infection developing in neutropenic infants.. Complete blood counts were performed on both cohorts and retrospectively evaluated. Neutropenia was diagnosed using published reference ranges for infants with birth weight less than or equal to 1500 g and > 1500 g. Evidence of nosocomial infection based on a positive blood culture with supportive clinical signs of sepsis was documented. The incidence of neutropenia among infants of hypertensive mothers was not significantly different from that among infants of normotensive mothers (21% vs 24%), but the duration of neutropenia was significantly longer in the infants of hypertensive mothers (P = 0.0001). Nosocomial infection was more frequent in neutropenic than the non-neutropenic hypertensive mothers' infants (55% vs 12%, P = 0.0002).
Keyword maternal hypertension
newborn
neutropenia
nosocomial infection
Colony-Stimulating Factor
Preeclampsia
Infants
Mothers
Q-Index Code C1
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: ResearcherID Downloads - Archived
 
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