Ultraviolet radiation of melanocytic nevi: a dermoscopic study

Hofmann-Wellenhof, Rainer, Soyer, H. Peter, Wolf, Ingrid H., Smolle, Josef, Reischle, Sebastian, Rieger, Edgar, Kenet, Robert O., Wolf, Peter and Kerl, Helmut (1998) Ultraviolet radiation of melanocytic nevi: a dermoscopic study. Archives of Dermatology, 134 7: 845-850. doi:10.1001/archderm.134.7.845


Author Hofmann-Wellenhof, Rainer
Soyer, H. Peter
Wolf, Ingrid H.
Smolle, Josef
Reischle, Sebastian
Rieger, Edgar
Kenet, Robert O.
Wolf, Peter
Kerl, Helmut
Title Ultraviolet radiation of melanocytic nevi: a dermoscopic study
Journal name Archives of Dermatology   Check publisher's open access policy
ISSN 0003-987X
2168-6084
Publication date 1998-07-01
Sub-type Article (original research)
DOI 10.1001/archderm.134.7.845
Open Access Status DOI
Volume 134
Issue 7
Start page 845
End page 850
Total pages 6
Place of publication Chicago, IL, United States
Publisher American Medical Association
Language eng
Formatted abstract
Background:  UV radiation can lead to clinical, histological, and ultrastructural changes in melanocytic nevi. In this study, we investigated whether exposure to 2 minimal erythema doses of UV radiation induces changes in the dermoscopic image of acquired melanocytic nevi.

Observations:  Fifteen melanocytic nevi were exposed to 2 minimal erythema doses of UV radiation. Differences in dermoscopic parameters (asymmetry, border, erythema, and telangiectasias in the nevus; pigmentation; hypopigmented areas; presence, regularity, and sharpness of pigment network; and brown-black globules) in digital dermoscopic images taken before and 3, 7, 14, and 28 days after UV irradiation were scored. Three days after UV irradiation, the borders of nevi were more faded (P<.02), the nevi were darker brown (P<.02), the hypopigmented areas were smaller (P<.02), and the pigment network structures were more faded (P<.007) and less prominent (P<.02) than before UV irradiation. Seven days after UV irradiation, pigmented globules have also grown (P<.05). After 28 days, all parameters, except hypopigmented areas, were essentially the same as before UV irradiation.

Conclusion:  UV irradiation of melanocytic nevi with 2 minimal erythema doses induces transient changes in their dermoscopic appearance that are sometimes suggestive of malignant melanoma.
Keyword Pigmented Skin-Lesions
Epiluminescence Microscopy
Surface Microscopy
Malignant-Melanoma
Seasonal-Variation
Nevocytic Nevi
Sun Exposure
Prevalence
Frequency
Diagnosis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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