Move it to improve it (Mitii): study protocol of a randomised controlled trial of a novel web-based multimodal training program for children and adolescents with cerebral palsy

Boyd, Roslyn N., Mitchell, Louise E., James, Sarah T., Ziviani, Jenny, Sakzewski, Leanne, Smith, Anthony, Rose, Stephen, Cunnington, Ross, Whittingham, Koa, Ware, Robert S., Comans, Tracey A. and Scuffham, Paul A. (2013) Move it to improve it (Mitii): study protocol of a randomised controlled trial of a novel web-based multimodal training program for children and adolescents with cerebral palsy. BMJ Open, 3 4: e002853.1-e002853.20. doi:10.1136/bmjopen-2013-002853

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Author Boyd, Roslyn N.
Mitchell, Louise E.
James, Sarah T.
Ziviani, Jenny
Sakzewski, Leanne
Smith, Anthony
Rose, Stephen
Cunnington, Ross
Whittingham, Koa
Ware, Robert S.
Comans, Tracey A.
Scuffham, Paul A.
Title Move it to improve it (Mitii): study protocol of a randomised controlled trial of a novel web-based multimodal training program for children and adolescents with cerebral palsy
Journal name BMJ Open   Check publisher's open access policy
ISSN 2044-6055
Publication date 2013-04-10
Sub-type Article (original research)
DOI 10.1136/bmjopen-2013-002853
Open Access Status DOI
Volume 3
Issue 4
Start page e002853.1
End page e002853.20
Total pages 20
Place of publication London, United Kingdom
Publisher B M J Group
Language eng
Abstract To examine the efficacy of a multi-modal web-based therapy program, Move it to improve it (Mitii™) delivered at home to improve Executive Functioning (EF) in children with an acquired brain injury (ABI).
Formatted abstract
Introduction: Persons with cerebral palsy require a lifetime of costly and resource intensive interventions which are often limited by equity of access. With increasing burden being placed on health systems, new methods to deliver intensive rehabilitation therapies are needed. Move it to improve it (Mitii) is an internet-based multimodal programme comprising upper-limb and cognitive training with physical activity. It can be accessed in the client's home at their convenience. The proposed study aims to test the efficacy of Mitii in improving upperlimb function and motor planning. Additionally, this study hopes to further our understanding of the central neurovascular mechanisms underlying the proposed changes and determine the cost effectiveness of Mitii.

Methods and analysis:
Children with congenital hemiplegia will be recruited to participate in this waitlist control, matched pairs, single-blind randomised trial. Children be matched at baseline and randomly allocated to receive 20 weeks of 30 min of daily Mitii training immediately, or waitlisted for 20 weeks before receiving the same Mitii training (potential total dose=70 h). Outcomes will be assessed at 20 weeks after the start of Mitii, and retention effects tested at 40 weeks. The primary outcomes will be the Assessment of Motor and Process Skills (AMPS), the Assisting Hand Assessment (AHA) and unimanual upper-limb capacity using the Jebsen-Taylor Test of Hand Function ( JTTHF). Advanced brain imaging will assess use-dependant neuroplasticity. Measures of body structure and functions, activity, participation and quality of life will be used to assess Mitii efficacy across all domains of the International Classification of Functioning, Disability and Health framework.

Ethics and dissemination: This project has received Ethics Approval from the Medical Ethics Committee of The University of Queensland (2011000608) and the Royal Children's Hospital Brisbane (HREC/11/QRCH/35). Findings will be disseminated widely through conference presentations, seminars and peer-reviewed scientific journals.

Trial registration: ACTRN12611001174976.
Keyword Executive functioning
RCT
acquired brain injury
children and adolescents
intervention
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number e002853

 
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Created: Tue, 28 May 2013, 19:41:28 EST by Ms Leanne Sakzewski on behalf of Paediatrics & Child Health - RBWH