Measurement of localized tissue water – clinical application of bioimpedance spectroscopy in wound management

Ward, L. C., Sharpe, K., Edgar, D., Finlay, V. and Wood, F. (2013) Measurement of localized tissue water – clinical application of bioimpedance spectroscopy in wound management. Journal of Physics: Conference Series, 434 1: 012043.1-012043.4. doi:10.1088/1742-6596/434/1/012043


Author Ward, L. C.
Sharpe, K.
Edgar, D.
Finlay, V.
Wood, F.
Title Measurement of localized tissue water – clinical application of bioimpedance spectroscopy in wound management
Journal name Journal of Physics: Conference Series   Check publisher's open access policy
ISSN 1742-6588
1742-6596
ISBN *****************
Publication date 2013-01-01
Sub-type Article (original research)
DOI 10.1088/1742-6596/434/1/012043
Open Access Status DOI
Volume 434
Issue 1
Start page 012043.1
End page 012043.4
Total pages 4
Place of publication Bristol, United Kingdom
Publisher Institute of Physics Publishing
Language eng
Abstract Wound healing is a complex process which can be impeded by the presence of accumulated cell fluid or oedema. A simple and convenient method for the assessment of wound oedema would aid improvement in patient care. In this proof of concept study we investigated whether bioelectrical impedance spectroscopy has the potential to provide such a tool. A number of important observations were made. Firstly, the method was highly reproducible and data can be obtained from electrodes located at different positions around the region of interest; important given the highly variable topography of surface wounds, e.g. burns. Secondly, the method was highly sensitive with the potential to detect changes of as little as 20 μl in extracellular fluid. Thirdly the relative changes in R0, R∞ and Ri following sub-cutaneous injections of saline were consistent with redistribution of water from the extracellular to intracellular space and /or removal from the local area as may occur during wound healing.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Chemistry and Molecular Biosciences
 
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Created: Fri, 26 Apr 2013, 19:52:18 EST by Mrs Louise Nimwegen on behalf of School of Chemistry & Molecular Biosciences