Dietary saturated fat and fibre and risk of cardiovascular disease and all-cause mortality among type 1 diabetic datients: the EURODIAB Prospective Complications Study

Schoenaker, D. A. J. M., Toeller, M., Chaturvedi, N., Fuller, J. H. and Soedamah-Muthu, S. S. (2012) Dietary saturated fat and fibre and risk of cardiovascular disease and all-cause mortality among type 1 diabetic datients: the EURODIAB Prospective Complications Study. Diabetologia, 55 8: 2132-2141. doi:10.1007/s00125-012-2550-0


Author Schoenaker, D. A. J. M.
Toeller, M.
Chaturvedi, N.
Fuller, J. H.
Soedamah-Muthu, S. S.
Title Dietary saturated fat and fibre and risk of cardiovascular disease and all-cause mortality among type 1 diabetic datients: the EURODIAB Prospective Complications Study
Journal name Diabetologia   Check publisher's open access policy
ISSN 0012-186X
1432-0428
Publication date 2012-04-12
Sub-type Article (original research)
DOI 10.1007/s00125-012-2550-0
Open Access Status Not yet assessed
Volume 55
Issue 8
Start page 2132
End page 2141
Total pages 10
Place of publication Heidelberg, Germany
Publisher Springer
Language eng
Formatted abstract
Aims/hypothesis: Low adherence to recommendations for dietary saturated fatty acid (SFA) and fibre intake in patients with type 1 diabetes mellitus may heighten their increased risk of cardiovascular disease (CVD) and mortality. We examined the relationship of SFA and total, soluble and insoluble fibre with incident CVD and all-cause mortality in type 1 diabetic patients.

Methods: A prospective cohort analysis was performed in 2,108 European type 1 diabetic patients aged 15-60 years who were free of CVD at baseline and enrolled in the EURODIAB Prospective Complications Study (51% male). Diet was assessed from a standardised 3 day dietary record. HR were calculated using Cox proportional hazards models.

Results: During a mean follow-up of 7.3 years, 148 incident cases of fatal and non-fatal CVD and 46 all-cause deaths were documented. No statistically significant association was found between SFA and CVD and all-cause mortality. Total dietary fibre, per 5 g/day, was associated with lower all-cause mortality risk (HR 0.72;95% CI 0.55, 0.95). This association was stronger for soluble fibre (per 5 g/day, HR 0.34;95% CI 0.14, 0.80) compared with insoluble fibre (per 5 g/day; HR 0.66;95% CI 0.45, 0.97). Similar results were found for the association with CVD.

Conclusions/interpretation: This study suggests that reported dietary SFA is not significantly associated with CVD and allcause mortality in type 1 diabetic patients. On the contrary, higher dietary fibre consumption, especially soluble fibre, within the range commonly consumed by type 1 diabetic patients, may contribute to the prevention of CVD and allcause mortality in type 1 diabetic patients.
Keyword All-cause mortality
Cardiovascular disease
Dietary fibre
Nutrition
Replacement of saturated fat
Saturated fat type 1 diabetes
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Published online: 12 April 2012.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Public Health Publications
 
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Created: Fri, 26 Apr 2013, 19:19:07 EST by Danielle Schoenaker on behalf of School of Public Health