Horn type and horn length genes map to the same chromosomal region in Soay sheep

Johnston, S. E., Beraldi, D., McRae, A. F., Pemberton, J. M. and Slate, J. (2010) Horn type and horn length genes map to the same chromosomal region in Soay sheep. Heredity, 104 2: 196-205. doi:10.1038/hdy.2009.109


Author Johnston, S. E.
Beraldi, D.
McRae, A. F.
Pemberton, J. M.
Slate, J.
Title Horn type and horn length genes map to the same chromosomal region in Soay sheep
Journal name Heredity   Check publisher's open access policy
ISSN 0018-067X
1365-2540
Publication date 2010-02-01
Year available 2009
Sub-type Article (original research)
DOI 10.1038/hdy.2009.109
Open Access Status Not Open Access
Volume 104
Issue 2
Start page 196
End page 205
Total pages 10
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Formatted abstract
The evolution of male weaponry in animals is driven by sexual selection, which is predicted to reduce the genetic variability underlying such traits. Soay sheep have an inherited polymorphism for horn type in both sexes, with males presenting with either large, normal horns or small, deformed horns (scurs). In addition, there is additive genetic variation in horn length among males with normal horns. Given that scurred males cannot win conflicts with normal-horned males, it is unusual that genes conferring scurs should persist in the population. Identifying the genetic basis of these traits should help us in understanding their evolution. We developed microsatellite markers in a targeted region of the Soay sheep genome and refined the location of the Horns locus (Ho) to a ~7.4 cM interval on chromosome 10 (LOD=8.78). We then located quantitative trait loci spanning a 34 cM interval with a peak centred close to Ho, which explained the majority of the genetic variation for horn length and base circumference in normal-horned males (LOD=2.51 and LOD=1.04, respectively). Therefore, the genetic variation in both horn type and horn length is attributable to the same chromosomal region. Understanding the maintenance of horn type and length variation will require an investigation of selection on genotypes that (co)determine both traits.
Keyword Quantitative trait locus mapping
Horn morphology
Natural population
Genetic correlation
Sexual selection
Trade-off
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Diamantina Institute Publications
 
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Created: Tue, 02 Apr 2013, 23:52:03 EST by Allan Mcrae on behalf of UQ Diamantina Institute