Genetic-Variants Within the Genus Echinococcus Identified by Mitochondrial-Dna Sequencing

Bowles, J, Blair, D and McManus, DP (1992) Genetic-Variants Within the Genus Echinococcus Identified by Mitochondrial-Dna Sequencing. Molecular and Biochemical Parasitology, 54 2: 165-174. doi:10.1016/0166-6851(92)90109-W

Author Bowles, J
Blair, D
McManus, DP
Title Genetic-Variants Within the Genus Echinococcus Identified by Mitochondrial-Dna Sequencing
Journal name Molecular and Biochemical Parasitology   Check publisher's open access policy
ISSN 0166-6851
Publication date 1992-09-01
Year available 1992
Sub-type Article (original research)
DOI 10.1016/0166-6851(92)90109-W
Open Access Status Not yet assessed
Volume 54
Issue 2
Start page 165
End page 174
Total pages 10
Place of publication AMSTERDAM
Language eng
Abstract The pattern of species and strain variation within the genus Echinococcus is complex and controversial. In an attempt to characterise objectively the various species and strains, the sequence of a region of the mitochondrial cytochrome c oxidase subunit I (CO1) gene was determined for 56 Echinococcus isolates. Eleven different genotypes were detected, including 7 within Echinococcus granulosus, and these were used to categorise the isolates. The 4 generally accepted Echinococcus species were dearly distinguishable using this approach. In addition, the consensus view of the strain pattern within E. granulosus, based on a variety of criteria of differentiation, was broadly upheld. Very little variation was detected within Echinococcus multilocularis. Remarkable intra-strain homogeneity was found at the DNA sequence level. This region of the rapidly evolving mitochondrial genome is useful as a marker of species and strain identity and as a preliminary indication of evolutionary divergence within the genus Echinococcus.
Keyword Echinococcus
Intraspecific Variation
Mitochondrial Dna
Cytochrome-C Oxidase-I
Direct Sequencing
Polymerase Chain Reaction
Granulosus Batsch
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: ResearcherID Downloads - Archived
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