Molecular Examination of the Sympatry and Distribution of Sheep and Camel Strains of Echinococcus-Granulosus in Kenya

Wachira, TM, Bowles, J, Zeyhle, E and McManus, DP (1993) Molecular Examination of the Sympatry and Distribution of Sheep and Camel Strains of Echinococcus-Granulosus in Kenya. American Journal of Tropical Medicine and Hygiene, 48 4: 473-479. doi:10.4269/ajtmh.1993.48.473


Author Wachira, TM
Bowles, J
Zeyhle, E
McManus, DP
Title Molecular Examination of the Sympatry and Distribution of Sheep and Camel Strains of Echinococcus-Granulosus in Kenya
Journal name American Journal of Tropical Medicine and Hygiene   Check publisher's open access policy
ISSN 0002-9637
Publication date 1993-04-01
Year available 1993
Sub-type Article (original research)
DOI 10.4269/ajtmh.1993.48.473
Open Access Status Not yet assessed
Volume 48
Issue 4
Start page 473
End page 479
Total pages 7
Place of publication MCLEAN
Publisher AMER SOC TROP MED & HYGIENE
Language eng
Abstract Previous studies have shown that camel and sheep strains of the cystic hydatid parasite Echinococcus granulosus occur in Kenya. We examined 208 larval isolates and 40 worm samples of E. granulosus from various hosts in Kenya using restriction fragment length polymorphism analysis of a segment of ribosomal DNA amplified by the polymerase chain reaction. This was in an effort to determine whether additional strains of E. granulosus occur in Kenya, to examine the level of genetic heterogeneity within the sheep/dog and camel/dog strains previously identified, and to map out their intermediate host range and geographic distribution in Kenya. We confirmed the existence of the two strains in Kenya and showed that the distribution of the camel strain appears restricted to the Turkana region, where camels are kept as livestock. The intermediate host range for both strains seems to be similar except that humans appear refractory to infection with the camel strain. We have also shown that although the life-cycle patterns of the two strains overlap both geographically and in intermediate and definitive hosts, the strains maintain their homogeneous genetic identity.
Keyword Turkana District
Hydatid-Disease
Hosts
Dogs
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: ResearcherID Downloads - Archived
 
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