The implementation of intravenous tissue plasminogen activator in acute ischaemic stroke - a scientific position statement from the National Stroke Foundation and the Stroke Society of Australasia

Ad Hoc Committee representing the National Stroke Foundation and the Stroke Society of Australasia, Levi, Christopher, Lindley, Richard, Smith, Brendon, Bladin, Christopher, Parsons, Mark, Read, Stephen, Cadilhac, Dominique, Donnan, Geoffrey, Davis, Stephen, Hankey, Graeme, Crimmins, Dennis, Gerraty, Richard, Blacker, David, Schultz, David, Grimley, Rohan and Lalor, Erin (2009) The implementation of intravenous tissue plasminogen activator in acute ischaemic stroke - a scientific position statement from the National Stroke Foundation and the Stroke Society of Australasia. Internal Medicine Journal, 39 5: 317-324. doi:10.1111/j.1445-5994.2009.01938.x


Author Ad Hoc Committee representing the National Stroke Foundation and the Stroke Society of Australasia
Levi, Christopher
Lindley, Richard
Smith, Brendon
Bladin, Christopher
Parsons, Mark
Read, Stephen
Cadilhac, Dominique
Donnan, Geoffrey
Davis, Stephen
Hankey, Graeme
Crimmins, Dennis
Gerraty, Richard
Blacker, David
Schultz, David
Grimley, Rohan
Lalor, Erin
Title The implementation of intravenous tissue plasminogen activator in acute ischaemic stroke - a scientific position statement from the National Stroke Foundation and the Stroke Society of Australasia
Journal name Internal Medicine Journal   Check publisher's open access policy
ISSN 1444-0903
1445-5994
Publication date 2009-05-01
Sub-type Article (original research)
DOI 10.1111/j.1445-5994.2009.01938.x
Volume 39
Issue 5
Start page 317
End page 324
Total pages 8
Place of publication Richmond, VIC, Australia
Publisher Wiley-Blackwell
Language eng
Abstract Intravenous tissue plasminogen activator (tPA) has been licensed in Australia for thrombolysis in selected patients with acute ischaemic stroke since 2003. The use of tPA is low but is increasing across Australia and national audits indicate efficacy and safety outcomes equivalent to international benchmarks. Implementing tPA therapy in clinical practice is, however, challenging and requires a coordinated multidisciplinary approach to acute stroke care across prehospital, emergency department and inpatient care sectors. Stroke care units are an essential ingredient underpinning safe implementation of stroke thrombolysis. Support systems such as care pathways, therapy delivery protocols, and thrombolysis-experienced multidisciplinary care teams are also important enablers. Where delivery of stroke thrombolysis is being planned, health systems need to be re-configured to provide these important elements. This consensus statement provides a review of the evidence for, and implementation of, tPA in acute ischaemic stroke with specific reference to the Australian health-care system.
Keyword Stroke
Cerebrovascular disease
Acute management
Thrombolysis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Ad Hoc Committee representing the National Stroke Foundation and the Stroke Society of Australasia.

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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