Bioelectrical impedance validation studies: alternative approaches to their interpretation

Ward, L. C. (2013) Bioelectrical impedance validation studies: alternative approaches to their interpretation. European Journal of Clinical Nutrition, 67 Supp S1: S10-S13. doi:10.1038/ejcn.2012.159

Author Ward, L. C.
Title Bioelectrical impedance validation studies: alternative approaches to their interpretation
Journal name European Journal of Clinical Nutrition   Check publisher's open access policy
ISSN 0954-3007
Publication date 2013-01-01
Year available 2013
Sub-type Article (original research)
DOI 10.1038/ejcn.2012.159
Open Access Status Not Open Access
Volume 67
Issue Supp S1
Start page S10
End page S13
Total pages 4
Place of publication London, United Kingdom
Publisher Nature
Language eng
Formatted abstract
Background/Objectives: Cross-validation of methods of body composition assessment necessitates statistical evaluation of the degree to which the two methods are in agreement. Typically, impedance-based methods for predicting body composition are assessed against other methods using limits of agreement and correlation analysis. Alternative approaches are presented with reference to example body composition data obtained using bioimpedance spectroscopy (BIS) and dual-energy X-ray absorptiometry (DXA).

Subjects/Methods: A randomly selected data set, drawn from a body composition database, was analysed by limits of agreement analysis and error grid analysis.

Results: The precision of BIS-derived predictions of percentage body fat relative to that of DXA can be determined from limits of agreement analysis. The importance of knowing the precision of the reference method in such analyses was highlighted. Error grid analysis has the potential to aid interpretation of method comparison data in an intuitively understandable way.

Conclusions: Alternative ways of comparing analytical methods that are in use in other branches of biomedical research may prove useful when evaluating the utility of impedance-based methods and other methods for the assessment of body composition in cross-validation studies.
Keyword Impedance analysis
Limits of agreement
Reference method precision
Error grids
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Chemistry and Molecular Biosciences
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Created: Fri, 18 Jan 2013, 23:38:14 EST by Mrs Louise Nimwegen on behalf of School of Chemistry & Molecular Biosciences