Effects of a supervised, outpatient exercise and physiotherapy programme in children with cystic fibrosis

Urquhart, Donald, Sell, Zoe, Dhouieb, Elaine, Bell, Gillian, Oliver, Sarah, Black, Ryan and Tallis, Matthew (2012) Effects of a supervised, outpatient exercise and physiotherapy programme in children with cystic fibrosis. Pediatric Pulmonology, 47 12: 1235-1241. doi:10.1002/ppul.22587


Author Urquhart, Donald
Sell, Zoe
Dhouieb, Elaine
Bell, Gillian
Oliver, Sarah
Black, Ryan
Tallis, Matthew
Title Effects of a supervised, outpatient exercise and physiotherapy programme in children with cystic fibrosis
Journal name Pediatric Pulmonology   Check publisher's open access policy
ISSN 8755-6863
1099-0496
Publication date 2012-12-01
Sub-type Article (original research)
DOI 10.1002/ppul.22587
Volume 47
Issue 12
Start page 1235
End page 1241
Total pages 7
Place of publication Hoboken, NJ United States
Publisher John Wiley and Sons
Collection year 2013
Language eng
Formatted abstract
Previous work suggests benefit from outpatient exercise and physiotherapy in children with cystic fibrosis (CF), namely improved exercise capacity and lung function measures, as well reduced intravenous (IV) antibiotic needs. Our study aim was to investigate the effect of a year-long supervised outpatient exercise and physiotherapy programme in children with CF. Subjects with CF aged â¥10 years who had received â¥4 courses of IV antibiotics in 2009 were enrolled and seen fortnightly for supervised exercise and physiotherapy throughout 2010. In addition, they were expected to exercise three times weekly, and if unwell complete additional physiotherapy sessions extra to usual chest physiotherapy. Assessments of exercise capacity using the Modified Shuttle Test (MST) and quality of life (QOL; CFQ-UK) were recorded at baseline and after 1 year. Regular spirometry was performed before and throughout the study. Data were collected on IV antibiotic days. 12 subjects (6 female) were enrolled with mean (95% CI) age of 13.3 (11.8-14.6) years at study entry. A significant reduction in IV antibiotic days from 60 (56-64) days in 2009 to 50 (44-56) in 2010 (P = 0.02) was noted, along with improved MST distance (m) [735 (603-867) vs. 943 (725-1,161), P = 0.04] and level attained [9.4 (8.4-10.5) vs. 11.1 (9.6-12.6), P = 0.04]. Significant improvements in CFQ-UK scores for physical [59 (47-72) vs. 83 (74-92), P = 0.001], emotional [63 (55-72) vs. 84 (74-93), P < 0.001], treatment [41 (30-51) vs. 61 (48-73), P = 0.002], and respiratory [54 (42-66) vs. 76 (70-82), P = 0.002] domains were noted. The mean (95% CI) rate of change of FEV1 was -4 (-18, +10)% in 2009, but was +6 (-2, +13)% in 2010, although this did not reach statistical significance. Supervised, outpatient exercise and physiotherapy are associated with improvements in QOL and exercise tolerance, a reduction in IV antibiotic days, and a trend towards reducing lung function decline in children with CF. The cost of IV antibiotics was reduced by £66,384 ($104,000) in 2010 when compared with 2009. Such cost-benefit may have implications for workforce planning and service provision.
Keyword Outpatient physiotherapy
Cystic Fibrosis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 12 times in Thomson Reuters Web of Science Article | Citations
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