Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production

Adarme-Vega, T. Catalina, Lim, David K. Y., Timmins, Matthew, Vernen, Felicitas, Li, Yan and Schenk, Peer M. (2012) Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production. Microbial Cell Factories, 11 96.1-96.10. doi:10.1186/1475-2859-11-96


Author Adarme-Vega, T. Catalina
Lim, David K. Y.
Timmins, Matthew
Vernen, Felicitas
Li, Yan
Schenk, Peer M.
Title Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production
Journal name Microbial Cell Factories   Check publisher's open access policy
ISSN 1475-2859
Publication date 2012-07-01
Year available 2012
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1186/1475-2859-11-96
Open Access Status DOI
Volume 11
Start page 96.1
End page 96.10
Total pages 10
Place of publication London, United Kingdom
Publisher BioMed Central
Language eng
Abstract Omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) provide significant health benefits and this has led to an increased consumption as dietary supplements. Omega-3 fatty acids EPA and DHA are found in animals, transgenic plants, fungi and many microorganisms but are typically extracted from fatty fish, putting additional pressures on global fish stocks. As primary producers, many marine microalgae are rich in EPA (C20:5) and DHA (C22:6) and present a promising source of omega-3 fatty acids. Several heterotrophic microalgae have been used as biofactories for omega-3 fatty acids commercially, but a strong interest in autotrophic microalgae has emerged in recent years as microalgae are being developed as biofuel crops. This paper provides an overview of microalgal biotechnology and production platforms for the development of omega-3 fatty acids EPA and DHA. It refers to implications in current biotechnological uses of microalgae as aquaculture feed and future biofuel crops and explores potential applications of metabolic engineering and selective breeding to accumulate large amounts of omega-3 fatty acids in autotrophic microalgae.
Keyword Docosahexaenoic acid
DHA
Eicosapentaenoic acid
EPA
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article # 96

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: School of Agriculture and Food Sciences
Official 2013 Collection
 
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