Comparison of magnetic resonance imaging-fluorodeoxyglucose positron emission tomography fusion with pathological staging in rectal cancer

Kam, M. H., Wong, D. C., Siu, S., Stevenson, A. R. L., Lai, J. and Phillips, G. E. (2010) Comparison of magnetic resonance imaging-fluorodeoxyglucose positron emission tomography fusion with pathological staging in rectal cancer. British Journal of Surgery, 97 2: 266-268. doi:10.1002/bjs.6866


Author Kam, M. H.
Wong, D. C.
Siu, S.
Stevenson, A. R. L.
Lai, J.
Phillips, G. E.
Title Comparison of magnetic resonance imaging-fluorodeoxyglucose positron emission tomography fusion with pathological staging in rectal cancer
Journal name British Journal of Surgery   Check publisher's open access policy
ISSN 0007-1323
1365-2168
Publication date 2010-02-01
Sub-type Article (original research)
DOI 10.1002/bjs.6866
Open Access Status
Volume 97
Issue 2
Start page 266
End page 268
Total pages 3
Place of publication Chichester, West Sussex, United Kingdom
Publisher John Wiley & Sons
Language eng
Formatted abstract
Background: This study represents an initial experience with combined magnetic resonance imaging (MRI) and [18F]fluorodeoxyglucose positron emission tomography (FDG PET) (MRI–PET fusion) in the primary staging of rectal carcinoma.

Methods: A retrospective analysis of data recorded on patients with rectal cancer was undertaken. Patients requiring long-course radiotherapy were excluded. Chest radiography, abdominal computed tomography and endorectal ultrasonography were performed. In addition, MRI of the pelvis, whole-body FDG PET and MRI–PET fusion were carried out. All patients subsequently underwent anterior resection.

Results: Twenty-three patients with rectal carcinoma (15 men), of median age 60 (range 46–75) years, were enrolled. In tumour (T) assessment, MRI correctly staged 14 of 22 T2/T3 tumours. In lymph node assessment, MRI–PET fusion had a sensitivity of 44 per cent, with a specificity and positive predictive value of 100 per cent. No additional information was acquired from MRI–PET fusion over MRI plus abdominal computed tomography and chest radiography.

Conclusion: MRI–PET fusion adds little to conventional investigations for staging rectal carcinoma.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Wed, 21 Nov 2012, 02:53:49 EST by Andrew Stevenson on behalf of Surgery - Royal Brisbane and Women's Hospital