Small bowel endoscopy and coeliac disease

Daveson, A. James M. and Anderson, Robert P. (2012) Small bowel endoscopy and coeliac disease. Best Practice and Research: Clinical Gastroenterology, 26 3: 315-323. doi:10.1016/j.bpg.2012.03.004

Author Daveson, A. James M.
Anderson, Robert P.
Title Small bowel endoscopy and coeliac disease
Journal name Best Practice and Research: Clinical Gastroenterology   Check publisher's open access policy
ISSN 1521-6918
Publication date 2012-06-01
Year available 2012
Sub-type Article (original research)
DOI 10.1016/j.bpg.2012.03.004
Open Access Status Not yet assessed
Volume 26
Issue 3
Start page 315
End page 323
Total pages 9
Editor Peter B. F. Mensink
Place of publication Oxford, United Kingdom
Publisher Bailliere Tindall
Language eng
Subject 2715 Gastroenterology
Abstract Coeliac disease (CD) is a gluten-responsive, chronic inflammatory enteropathy that shares many features with classical autoimmune diseases. Coeliac disease affects about 1–2% of Caucasians, North Africans and Asians who possess the necessary susceptibility genes encoding HLA DQ2 or HLA DQ8. It is not only unique among the autoimmune diseases in that the precise trigger (gluten from wheat, rye and barley) has been identified, but also in that it has lent itself well to advancements in endoscopic imaging. Since its introduction, flexible endoscopy has allowed tissue to be collected from the small bowel with relative ease and safety, and recently has facilitated direct imaging and sampling of the entire small intestine. It is now fifty years since the Crosby capsule first allowed clinicians the ability to non-surgically biopsy the small bowel leading to an enhanced diagnosis of coeliac disease. The introduction of wireless video capsule endoscopy (VCE), small bowel enteroscopy and in particular double balloon enteroscopy (DBE), have expedited the accurate diagnosis of coeliac disease and its more serious complications such as small bowel adenocarcinoma, refractory coeliac disease type II (RCDII) and enteropathy associated T cell lymphoma (EATL).
Keyword Coeliac disease
Double balloon enteroscopy
Refractory coeliac disease
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Special issue: Small Bowel Endoscopy

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
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