Axon guidance

Piper, Michael J., Keynes, Roger J. and Cook, Geoffrey M. W. (2012). Axon guidance. In eLS (pp. 1-8) London, United Kingdom: John Wiley & Sons. doi:10.1002/9780470015902.a0000799.pub3

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Author Piper, Michael J.
Keynes, Roger J.
Cook, Geoffrey M. W.
Title of chapter Axon guidance
Title of book eLS
Place of Publication London, United Kingdom
Publisher John Wiley & Sons
Publication Year 2012
Sub-type Chapter in reference work, encyclopaedia, manual or handbook
DOI 10.1002/9780470015902.a0000799.pub3
Open Access Status
ISBN 9780470015902
Chapter number 328
Start page 1
End page 8
Total pages 8
Collection year 2013
Language eng
Abstract/Summary The establishment of complex neuronal circuits is critically dependent on axon guidance. The function of differentiated neurons is predicated on correct axon guidance, and is usually distinguished from the subsequent developmental stages of target recognition and synapse formation. In large measure it involves the axon growth cone, the terminal expansion at the end of growing axons. Two aspects of growth cone function are particularly relevant: its ability to locomote, and its capacity to detect environmental cues and transduce them into signals that determine the direction and rate of axonal growth.
Keyword Axon guidance
Q-Index Code BX
Q-Index Status Confirmed Code
Institutional Status UQ

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Created: Thu, 26 Jul 2012, 12:37:21 EST by Dr Michael Piper on behalf of School of Biomedical Sciences