Risk of hip fracture with hip or knee osteoarthritis: a systematic review

Chudyk, Anna M., Ashe, Maureen C., Gorman, Erin, Al Tunaiji, Hashel O. and Crossley, Kay M. (2012) Risk of hip fracture with hip or knee osteoarthritis: a systematic review. Clinical Rheumatology, 31 5: 749-757. doi:10.1007/s10067-012-1970-z

Author Chudyk, Anna M.
Ashe, Maureen C.
Gorman, Erin
Al Tunaiji, Hashel O.
Crossley, Kay M.
Title Risk of hip fracture with hip or knee osteoarthritis: a systematic review
Journal name Clinical Rheumatology   Check publisher's open access policy
ISSN 0770-3198
Publication date 2012-05-01
Year available 2012
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s10067-012-1970-z
Volume 31
Issue 5
Start page 749
End page 757
Total pages 9
Place of publication Guildford, Surrey, United Kingdom
Publisher Springer
Language eng
Abstract Osteoarthritis (OA) and hip fracture are two common musculoskeletal disorders associated with substantial societal and personal burden. The objective of this systematic review was to determine the association between hip or knee OA and risk of hip fractures in people aged 45 years and older as compared to people aged 45 years and older who do not have OA. We searched CINAHL, Cochrane Database of Systematic Reviews, Embase, OVID Medline, PUBMED, and SCOPUS for studies published up to July 2010 and conducted forward searches of included studies using Web of Science. Two reviewers independently screened articles for inclusion, extracted data, and evaluated the risk of bias of included studies using the Newcastle-Ottawa Scale. Eleven articles were included. Three investigated individuals with knee OA, two included adults with knee or hip OA, and six investigated adults with hip OA. We did not combine the hip OA or the knee OA studies in a meta-analysis due to the heterogeneity in: study populations and covariates adjusted for in estimates of association. Hip OA may be related to a decreased risk of hip fracture when considering crude estimates of association or estimates of association adjusted for a limited number of covariates, although not all studies found support for the presence of this association. The association between knee OA and hip fracture remains unclear. The presence of OA in the hip or knee should not act as an indication that assessment for hip fracture risk is unnecessary.
Keyword Hip fracture
Hip fracture risk
Systematic review
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID 105803-1
Institutional Status UQ
Additional Notes Published online: 16 March 2012.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2013 Collection
School of Health and Rehabilitation Sciences Publications
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