The impact of peripheral arterial disease on health-related quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) Program

Regensteiner, Judith G., Hiatt, William R., Coll, Joseph R., Criqui, Michael H, Treat-Jacobson, Diane, McDermott, Mary M. and Hirsch, Alan T. (2008) The impact of peripheral arterial disease on health-related quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) Program. Vascular Medicine, 13 1: 15-24. doi:10.1177/1358863X07084911


Author Regensteiner, Judith G.
Hiatt, William R.
Coll, Joseph R.
Criqui, Michael H
Treat-Jacobson, Diane
McDermott, Mary M.
Hirsch, Alan T.
Title The impact of peripheral arterial disease on health-related quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) Program
Journal name Vascular Medicine   Check publisher's open access policy
ISSN 1358-863X
1477-0377
Publication date 2008-02-01
Sub-type Article (original research)
DOI 10.1177/1358863X07084911
Open Access Status Not Open Access
Volume 13
Issue 1
Start page 15
End page 24
Total pages 10
Place of publication London, United Kingdom
Publisher Sage Publications
Language eng
Abstract This study tested the hypothesis that patients with PAD have impaired health-related quality of life (HRQoL) to a degree similar to that of patients with other types of cardiovascular disease (other-CVD), and also evaluated the clinical features of PAD associated with impaired HRQoL. This was a cross-sectional study in 350 primary care practice sites nationwide with 6,499 participants. The reference group had no clinical or hemodynamic evidence of PAD or other-CVD; the PAD group had an ankle-brachial index < 0.90 or a prior history of PAD; the other-CVD group had a clinical history of cardiac or cerebral vascular disease (but no PAD), and the combined PAD-other-CVD group included both diagnoses. Individuals were assessed using four HRQoL questionnaires including the Walking Impairment Questionnaire (WIQ), Medical Outcomes Study SF-36 (SF-36), Cantril Ladder of Life and the PAD Quality of Life questionnaire. PAD patients had lower WIQ distance scores than the other-CVD group. Both the PAD and other-CVD groups had significantly lower SF-36 Physical Function scores compared with the reference group. The WIQ revealed that PAD patients were more limited by calf pain, whereas other-CVD patients were more limited by chest pain, shortness of breath and palpitations. In conclusion, in this nationwide study, one of the first to directly compare the HRQoL burden of CVD with that of PAD, the evaluation of PAD in office practice revealed a HRQoL burden as great in magnitude as in patients with other forms of CVD.
Keyword Cardiovascular disease
Claudication
Functional status
Health-related quality of life
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Public Health Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 104 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 126 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 03 Apr 2012, 00:45:59 EST by System User on behalf of School of Public Health