The association between infant feeding practices and subsequent atopy among children with a family history of asthma

Mihrshahi, S., Ampon, R., Webb, K., Almqvist, C., Kemp, A. S., Hector, D., Marks, G. B. and CAPS Team (2007) The association between infant feeding practices and subsequent atopy among children with a family history of asthma. Clinical and Experimental Allergy, 37 5: 671-679. doi:10.1111/j.1365-2222.2007.02696.x


Author Mihrshahi, S.
Ampon, R.
Webb, K.
Almqvist, C.
Kemp, A. S.
Hector, D.
Marks, G. B.
CAPS Team
Title The association between infant feeding practices and subsequent atopy among children with a family history of asthma
Journal name Clinical and Experimental Allergy   Check publisher's open access policy
ISSN 0954-7894
1365-2222
Publication date 2007-05-01
Year available 2007
Sub-type Article (original research)
DOI 10.1111/j.1365-2222.2007.02696.x
Open Access Status Not yet assessed
Volume 37
Issue 5
Start page 671
End page 679
Total pages 9
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell Publishing
Language eng
Formatted abstract
Background Although longer duration of breastfeeding and later introduction of solid foods are both recommended for the prevention of asthma and allergic disease, evidence to support these recommendations is controversial.
Objective To examine the relation between infant feeding practices and the risk of asthma and allergic disease at age 5 years.
Methods A cohort of children with a family history of asthma in Sydney, Australia, was followed from birth to age 5 years. Data on infant feeding practices and on early manifestations of eczema were collected prospectively. The presence of eczema, asthma and atopy (positive allergen skin prick tests) were determined at age 5 years.
Results In 516 children evaluated at age 5 years, there was no significant association between the duration of breastfeeding or timing of introduction of solid foods and protection against asthma or other allergic disease, after adjustment for confounding factors. However, breastfeeding for 6 months or more and introduction of solid foods after 3 months were both associated with an increased risk of atopy at age 5 years (P=0.02 and 0.01, respectively). There was no significant association between the presence of eczema at 4 weeks and at 3 months and continued breastfeeding beyond those times.
Conclusion Longer duration of breastfeeding and later introduction of solid foods did not prevent the onset of asthma, eczema or atopy by age 5 years.
Keyword Asthma
Atopy
Breastfeeding
Eczema
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Public Health Publications
 
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