Intact language skills and semantic processing speed following the use of fractionated cranial irradiation therapy for the treatment of childhood medulloblastoma: A 4-year follow-up study

Lewis, Fiona M. and Murdoch, Bruce E. (2011) Intact language skills and semantic processing speed following the use of fractionated cranial irradiation therapy for the treatment of childhood medulloblastoma: A 4-year follow-up study. Neurocase, 17 4: 332-344. doi:10.1080/13554794.2010.509323


Author Lewis, Fiona M.
Murdoch, Bruce E.
Title Intact language skills and semantic processing speed following the use of fractionated cranial irradiation therapy for the treatment of childhood medulloblastoma: A 4-year follow-up study
Journal name Neurocase   Check publisher's open access policy
ISSN 1355-4794
1465-3656
Publication date 2011-01-01
Year available 2011
Sub-type Article (original research)
DOI 10.1080/13554794.2010.509323
Open Access Status Not yet assessed
Volume 17
Issue 4
Start page 332
End page 344
Total pages 13
Place of publication Sussex, England, U.K.
Publisher Psychology Press
Language eng
Subject 2728 Clinical Neurology
Abstract Recent advances in the delivery of cranial radiation therapy aim to reduce the adverse neurocognitive outcomes associated with successful treatments. Damage to white matter tracts following cranial radiation may result in a reduction in information processing speed, which in turn may lead to declines in academic achievement and performance scores on neurocognitive testing. This study reports on language outcomes and neurophysiological measures reflecting the efficiency of the brain's capacity to process semantic information in a 14-year-old female following treatment, which included fractionated cranial radiation dosages, for medulloblastoma at age 10 years 3 months. The findings suggest processing skills on par with her peers and stability in general language skill over the 4 years post-treatment.
Keyword Language outcomes
Semantic processing
Fractionated cranial irradiation
Medulloblastoma
Posterior-Fossa Tumors
Quality-of-Life
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
School of Health and Rehabilitation Sciences Publications
 
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