FishNet: An online database of zebrafish anatomy

Bryson-Richardson, Robert J., Berger, Silke, Schilling, Thomas F., Hall, Thomas E., Cole, Nicholas J., Gibson, Abigail J., Sharpe, James and Currie, Peter D. (2007) FishNet: An online database of zebrafish anatomy. BMC Biology, 5 34.1-34.8. doi:10.1186/1741-7007-5-34

Author Bryson-Richardson, Robert J.
Berger, Silke
Schilling, Thomas F.
Hall, Thomas E.
Cole, Nicholas J.
Gibson, Abigail J.
Sharpe, James
Currie, Peter D.
Title FishNet: An online database of zebrafish anatomy
Journal name BMC Biology   Check publisher's open access policy
ISSN 1741-7007
Publication date 2007-08-01
Year available 2007
Sub-type Article (original research)
DOI 10.1186/1741-7007-5-34
Open Access Status DOI
Volume 5
Start page 34.1
End page 34.8
Total pages 8
Place of publication London, United Kingdom
Publisher BioMed Central
Language eng
Formatted abstract
Background: Over the last two decades, zebrafish have been established as a genetically versatile model system for investigating many different aspects of vertebrate developmental biology. With the credentials of zebrafish as a developmental model now well recognized, the emerging new opportunity is the wider application of zebrafish biology to aspects of human disease modelling. This rapidly increasing use of zebrafish as a model for human disease has necessarily generated interest in the anatomy of later developmental phases such as the larval, juvenile, and adult stages, during which many of the key aspects of organ morphogenesis and maturation take place. Anatomical resources and references that encompass these stages are non-existent in zebrafish and there is therefore an urgent need to understand how different organ systems and anatomical structures develop throughout the life of the fish.
Results: To overcome this deficit we have utilized the technique of optical projection tomography to produce three-dimensional (3D) models of larval fish. In order to view and display these models we have created FishNet webcite, an interactive reference of zebrafish anatomy spanning the range of zebrafish development from 24 h until adulthood.
Conclusion: FishNet contains more than 36 000 images of larval zebrafish, with more than 1 500 of these being annotated. The 3D models can be manipulated on screen or virtually sectioned. This resource represents the first complete embryo to adult atlas for any species in 3D.
Keyword Biology
Life Sciences & Biomedicine - Other Topics
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID MC_U127574434
R01 NS041353
Institutional Status Non-UQ
Additional Notes Article # 34

Document type: Journal Article
Sub-type: Article (original research)
Collections: ERA 2012 Admin Only
Institute for Molecular Bioscience - Publications
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Citation counts: TR Web of Science Citation Count  Cited 37 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 42 times in Scopus Article | Citations
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Created: Tue, 07 Feb 2012, 20:35:57 EST by Susan Allen on behalf of Institute for Molecular Bioscience