Detection limits in whispering gallery biosensors with plasmonic enhancement

Swaim, Jon D., Knittel, Joachim and Bowen, Warwick P. (2011) Detection limits in whispering gallery biosensors with plasmonic enhancement. Applied Physics Letters, 99 24: 243109.1-243109.3. doi:10.1063/1.3669398

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Author Swaim, Jon D.
Knittel, Joachim
Bowen, Warwick P.
Title Detection limits in whispering gallery biosensors with plasmonic enhancement
Journal name Applied Physics Letters   Check publisher's open access policy
ISSN 0003-6951
1077-3118
Publication date 2011-12-12
Year available 2011
Sub-type Article (original research)
DOI 10.1063/1.3669398
Open Access Status File (Publisher version)
Volume 99
Issue 24
Start page 243109.1
End page 243109.3
Total pages 3
Place of publication College Park, MD, United States
Publisher American Institute of Physics
Language eng
Abstract We perform numerical modeling of a gold nanorod bound to the surface of a microtoroid-based biosensor. Localized surface plasmon resonances in the nanorod give rise to strong enhancements in the electric field when excited near resonance, increasing the frequency shift for a single bovine serum albumin molecule by a factor of 870, with even larger enhancements predicted for smaller proteins. On resonance, the frequency shift is predicted to be on the order of MHz, more than an order of magnitude larger than measurement noise arising from time-averaged frequency and thermal fluctuations.
Keyword Physics, Applied
Physics
PHYSICS, APPLIED
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID DP0987146
Institutional Status UQ
Additional Notes Article # 243109

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mathematics and Physics
Official 2012 Collection
 
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