Diffusion-weighted imaging in the prostate: An apparent diffusion coefficient comparison of half-Fourier acquisition single-shot turbo spin-echo and echo planar imaging

Babourina-Brooks, Ben, Cowin, Gary J. and Wang, Deming (2012) Diffusion-weighted imaging in the prostate: An apparent diffusion coefficient comparison of half-Fourier acquisition single-shot turbo spin-echo and echo planar imaging. Magnetic Resonance Imaging, 30 2: 189-194. doi:10.1016/j.mri.2011.09.024


Author Babourina-Brooks, Ben
Cowin, Gary J.
Wang, Deming
Title Diffusion-weighted imaging in the prostate: An apparent diffusion coefficient comparison of half-Fourier acquisition single-shot turbo spin-echo and echo planar imaging
Journal name Magnetic Resonance Imaging   Check publisher's open access policy
ISSN 0730-725X
1873-5894
Publication date 2012-01-01
Year available 2011
Sub-type Article (original research)
DOI 10.1016/j.mri.2011.09.024
Volume 30
Issue 2
Start page 189
End page 194
Total pages 6
Place of publication Philadelphia, PA, United States
Publisher Elsevier
Collection year 2012
Language eng
Formatted abstract
Prostate cancer detection using diffusion-weighted imaging is highly affected by the accuracy of the apparent diffusion coefficient (ADC) values in an image. Echo planar imaging (EPI) is a fast sequence commonly used for diffusion imaging but has inherent magnetic susceptibility and chemical shift artefacts associated. A diffusion sequence that is less affected by these artefacts is therefore advantageous. The half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequence was chosen. The diffusion sequences were compared in image quality, repeatability of the ADC value and the effect on the ADC value with varied b values. Eight volunteers underwent three scans of each sequence, on a 1.5-T Siemens system, using b values of 0, 150, 300, 450, 600, 750, 900 and 1000 s/mm2. ADC maps were created to address the reproducibility of the ADC value when using two b values compared to eight b values. The ADC value using all b values with the HASTE sequence gave the best performance in all tested categories. Both sequences gave significantly different ADC mean values for two b values compared to when using eight b values (P<.05) suggesting larger error is present when using two b values. HASTE was shown to be an improvement over EPI in terms of repeatability, signal variation within a region of interest and standard deviation over the volunteer set. The improved accuracy of the ADC value in the HASTE sequence makes it potentially a more sensitive tumor detection technique.
Keyword Prostacyclin
Diffusion
ADC
b value
DWI
EPI
HASTE
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2012 Collection
Centre for Advanced Imaging Publications
 
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Created: Wed, 30 Nov 2011, 23:38:25 EST by Sandrine Ducrot on behalf of Centre for Advanced Imaging