Successful treatment of disseminated Scedosporium infection in 2 lung transplant recipients: Review of the literature and recommendations for management

Musk, M, Chambers, D, Chin, W, Murray, R and Gabbay, E (2006) Successful treatment of disseminated Scedosporium infection in 2 lung transplant recipients: Review of the literature and recommendations for management. Journal of Heart and Lung Transplantation, 25 10: 1268-1272. doi:10.1016/j.healun.2006.06.002


Author Musk, M
Chambers, D
Chin, W
Murray, R
Gabbay, E
Title Successful treatment of disseminated Scedosporium infection in 2 lung transplant recipients: Review of the literature and recommendations for management
Journal name Journal of Heart and Lung Transplantation   Check publisher's open access policy
ISSN 1053-2498
Publication date 2006-10-01
Year available 2006
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.healun.2006.06.002
Open Access Status Not Open Access
Volume 25
Issue 10
Start page 1268
End page 1272
Total pages 5
Place of publication NEW YORK
Publisher ELSEVIER SCIENCE INC
Language eng
Abstract Non-typhoidal Salmonellae are a major cause of infectious diarrhoea worldwide and can cause invasive diseases, including bacteraemia, meningitis and osteomyelitis. Young or immunocompromised children and those with underlying conditions such as sickle cell disease are particularly vulnerable to invasive disease. There has been an increase in the rate of resistant non-typhoidal Salmonella, which is associated with invasive disease and hospitalisation. The intracellular nature of non-typhoidal Salmonella protects against extracellular antibiotics and can facilitate disease relapse, particularly meningitis. Effective antimicrobial agents with good intracellular penetration include azithromycin, fluoroquinolones and third-generation cephalosporins. Antibiotic treatment of non-typhoidal Salmonella gastroenteritis is only indicated if there are risk factors for invasive disease as it can prolong excretion and does not shorten the duration of gastrointestinal symptoms. Optimal choice and length of therapy for gastroenteritis and invasive disease in children is not clear. Here, we provide a review of the literature and treatment recommendations.
Keyword Antifungal Agent
Apiospermum
Prolificans
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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