Comparative metagenomics of microbial communities

Tringe, Susannah Green, von Mering, Christian, Kobayashi, Arthur, Salamov, Asaf A., Chen, Kevin, Chang, Hwai W., Podar, Mircea, Short, Jay M., Mathur, Eric J., Detter, John C., Bork, Peer, Hugenholtz, Philip and Rubin, Edward M. (2005) Comparative metagenomics of microbial communities. Science, 308 5721: 554-557. doi:10.1126/science.1107851

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Author Tringe, Susannah Green
von Mering, Christian
Kobayashi, Arthur
Salamov, Asaf A.
Chen, Kevin
Chang, Hwai W.
Podar, Mircea
Short, Jay M.
Mathur, Eric J.
Detter, John C.
Bork, Peer
Hugenholtz, Philip
Rubin, Edward M.
Title Comparative metagenomics of microbial communities
Journal name Science   Check publisher's open access policy
ISSN 0036-8075
Publication date 2005-04-22
Year available 2005
Sub-type Article (original research)
DOI 10.1126/science.1107851
Open Access Status Not yet assessed
Volume 308
Issue 5721
Start page 554
End page 557
Total pages 4
Place of publication Washington, DC, United States
Publisher American Association for the Advancement of Science
Language eng
Abstract The species complexity of microbial communities and challenges in culturing representative isolates make it difficult to obtain assembled genomes. Here we characterize and compare the metabolic capabilities of terrestrial and marine microbial communities using largely unassembled sequence data obtained by shotgun sequencing DNA isolated from the various environments. Quantitative gene content analysis reveals habitat-specific fingerprints that reflect known characteristics of the sampled environments. The identification of environment-specific genes through a gene-centric comparative analysis presents new opportunities for interpreting and diagnosing environments.
Keyword Genome
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: ERA 2012 Admin Only
School of Chemistry and Molecular Biosciences
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Citation counts: TR Web of Science Citation Count  Cited 908 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 957 times in Scopus Article | Citations
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Created: Mon, 28 Nov 2011, 19:01:56 EST by Hong Lee on behalf of School of Chemistry & Molecular Biosciences