The effects of vitamin D on brain development and adult brain function

James Kesby, Eyles, Darryl, Burne, Thomas H.J. and McGrath, John J. (2011) The effects of vitamin D on brain development and adult brain function. Molecular and Cellular Endocrinology, 347 1-2: 121-127. doi:10.1016/j.mce.2011.05.014

Author James Kesby
Eyles, Darryl
Burne, Thomas H.J.
McGrath, John J.
Title The effects of vitamin D on brain development and adult brain function
Journal name Molecular and Cellular Endocrinology   Check publisher's open access policy
ISSN 0303-7207
Publication date 2011-12-05
Year available 2011
Sub-type Article (original research)
DOI 10.1016/j.mce.2011.05.014
Open Access Status Not yet assessed
Volume 347
Issue 1-2
Start page 121
End page 127
Total pages 7
Editor Howard Morris
Paul Anderson
Place of publication Shannon, Co. Clare, Ireland
Publisher Elsevier Ireland
Language eng
Subject 1310 Endocrinology
1312 Molecular Biology
1303 Biochemistry
Abstract A role for vitamin D in brain development and function has been gaining support over the last decade. Multiple lines of evidence suggest that this vitamin is actually a neuroactive steroid that acts on brain development, leading to alterations in brain neurochemistry and adult brain function. Early deficiencies have been linked with neuropsychiatric disorders, such as schizophrenia, and adult deficiencies have been associated with a host of adverse brain outcomes, including Parkinson’s disease, Alzheimer’s disease, depression and cognitive decline. This review summarises the current state of research on the actions of vitamin D in the brain and the consequences of deficiencies in this vitamin. Furthermore, we discuss specific implications of vitamin D status on the neurotransmitter, dopamine.
Keyword Vitamin D
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Special issue - Vitamin D Metabolism: Implication for Biological Activities

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2012 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 72 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 79 times in Scopus Article | Citations
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Created: Sat, 12 Nov 2011, 01:40:49 EST by Debra McMurtrie on behalf of Queensland Brain Institute