Acute twin-twin transfusion: a possible mechanism for brain-damaged survivors after intrauterine death of a monochorionic twin

Fusi, L., McParland, P., Fisk, N.M., Nicolini, U. and Wigglesworth, J. (1991) Acute twin-twin transfusion: a possible mechanism for brain-damaged survivors after intrauterine death of a monochorionic twin. Obstetrics and Gynecology, 78 3: 517-520.

Author Fusi, L.
McParland, P.
Fisk, N.M.
Nicolini, U.
Wigglesworth, J.
Title Acute twin-twin transfusion: a possible mechanism for brain-damaged survivors after intrauterine death of a monochorionic twin
Journal name Obstetrics and Gynecology   Check publisher's open access policy
ISSN 0029-7844
1873-233X
Publication date 1991-09-01
Year available 1991
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 78
Issue 3
Start page 517
End page 520
Total pages 4
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Abstract Intrauterine death of one twin in monochorionic pregnancies is associated with increased mortality and morbidity for the survivor. This has been attributed to the consequences of intrauterine disseminated intravascular coagulation (DIC) initiated by the dead twin. We describe a case in which the fetal cerebral and renal lesions typically found in survivors occurred without any derangement in coagulation. Instead, acute twin-twin transfusion was suggested by the presence of severe anemia in the surviving fetus at delivery. We suggest that the lesions frequently found in the survivors are often due to acute hemodynamic and ischemic changes resulting from acute twin-twin transfusion at the time of intrauterine death, rather than to late-onset DIC. This hypothesis has an important implication for future management: Intervention must occur before intrauterine death if neurologic sequelae in the survivor are to be prevented.
Keyword Multiple gestation
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Faculty of Health and Behavioural Sciences -- Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 144 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 167 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 25 Oct 2011, 03:35:22 EST by System User on behalf of Faculty Of Health Sciences