Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies

Liu, Yong, Wang, Kun, Yu, Chunshui, He, Yong, Zhou, Yuan, Liang, Meng, Wang, Liang and Jiang, Tianzi (2008) Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies. Neuropsychologia, 46 6: 1648-1656. doi:10.1016/j.neuropsychologia.2008.01.027


Author Liu, Yong
Wang, Kun
Yu, Chunshui
He, Yong
Zhou, Yuan
Liang, Meng
Wang, Liang
Jiang, Tianzi
Title Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies
Journal name Neuropsychologia   Check publisher's open access policy
ISSN 0028-3932
1873-3514
Publication date 2008-02-14
Sub-type Article (original research)
DOI 10.1016/j.neuropsychologia.2008.01.027
Volume 46
Issue 6
Start page 1648
End page 1656
Total pages 9
Place of publication Oxford, United Kingdom
Publisher Pergamon
Language eng
Formatted abstract
Resting-state functional magnetic resonance imaging (fMRI), a promising technique for measuring brain activities during rest, has attracted much attention in the past few years. In this paper, we review recent progress on the study of Alzheimer's disease (AD) based on resting-state fMRI. First, we briefly introduce some AD-related studies from other groups. Then we describe our AD-related work in detail from three aspects: (1) alterations in regional homogeneity (ReHo) of the fMRI signal in the resting state, (2) altered patterns of functional connectivity from regions of interest and whole brain analyses, and (3) discriminative analyses based on classification features from resting-state fMRI data for differentiating AD patients from healthy elders. Finally, we summarize the main results and some prospects for future work.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
ERA 2012 Admin Only
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 116 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 135 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 21 Oct 2011, 01:00:53 EST by Debra McMurtrie on behalf of Queensland Brain Institute