Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris

Reed, R.P., CookeYarborough, C.M., Jaquiery, A.L., Grimwood, K., Kemp, A.S., Su, J.C. and Forsyth, J.R.L. (1997) Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris. Medical Journal of Australia, 167 2: 82-84.

Author Reed, R.P.
CookeYarborough, C.M.
Jaquiery, A.L.
Grimwood, K.
Kemp, A.S.
Su, J.C.
Forsyth, J.R.L.
Title Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris
Journal name Medical Journal of Australia   Check publisher's open access policy
ISSN 0025-729X
1326-5377
Publication date 1997-07-01
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 167
Issue 2
Start page 82
End page 84
Total pages 3
Place of publication Strawberry Hills, Australia
Publisher Australasian Medical Publishing Company
Language eng
Formatted abstract
Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is rare (63 human cases reported worldwide) and fatal. We report a case in a five-year-old boy who had previously been well. For 18 months, he had had a slowly progressive, granulomatous mid facial lesion, but despite extensive investigation definitive diagnosis was made only with the acute onset of neurological signs in the last two weeks of life, when a brain biopsy specimen revealed amoebic trophozoites and cysts. Infection with B. mandrillaris should be considered in the differential diagnosis of chronic skin lesions with non-specific granulomatous histopathology and negative microbiological test results.
Keyword Amebic meningoencephalitis
Agent
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Child Health Research Centre Publications
 
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