The Presence of Serotonin (5-Ht(1)) Receptors Negatively Coupled to Adenylate-Cyclase in Rabbit and Human Iris-Ciliary Processes

Barnett, NL and Osborne, NN (1993) The Presence of Serotonin (5-Ht(1)) Receptors Negatively Coupled to Adenylate-Cyclase in Rabbit and Human Iris-Ciliary Processes. Experimental Eye Research, 57 2: 209-216. doi:10.1006/exer.1993.1116


Author Barnett, NL
Osborne, NN
Title The Presence of Serotonin (5-Ht(1)) Receptors Negatively Coupled to Adenylate-Cyclase in Rabbit and Human Iris-Ciliary Processes
Journal name Experimental Eye Research   Check publisher's open access policy
ISSN 0014-4835
Publication date 1993-08-01
Year available 1993
Sub-type Article (original research)
DOI 10.1006/exer.1993.1116
Open Access Status Not Open Access
Volume 57
Issue 2
Start page 209
End page 216
Total pages 8
Place of publication LONDON
Publisher ACADEMIC PRESS LTD
Language eng
Abstract The Gq-coupled 5-hydroxytryptamine 2B (5-HT2B) receptor is known to regulate the proliferation of islet beta cells during pregnancy. However, the role of serotonin in the control of insulin release is still controversial. The aim of the present study was to explore the role of the 5-HT2B receptor in the regulation of insulin secretion in mouse and human islets, as well as in clonal INS-1(832/13) cells.
Keyword Serotonin
5-Ht(1)
Iris
Ciliary Processes
Cyclic Amp
Rabbit
Human
Binding-Sites
5-Ht1d Receptors
Cyclic-Amp
5-Hydroxytryptamine
Inhibition
Subtypes
Body
Stimulation
Forskolin
Identification
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: ResearcherID Downloads - Archived
 
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