Cell Biology of Neuronal Endocytosis

Parton, R. G. and Dotti, C. G. (1993) Cell Biology of Neuronal Endocytosis. Journal of Neuroscience Research, 36 1: 1-9. doi:10.1002/jnr.490360102


Author Parton, R. G.
Dotti, C. G.
Title Cell Biology of Neuronal Endocytosis
Journal name Journal of Neuroscience Research   Check publisher's open access policy
ISSN 0360-4012
Publication date 1993-09-01
Year available 1993
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/jnr.490360102
Open Access Status Not yet assessed
Volume 36
Issue 1
Start page 1
End page 9
Total pages 9
Place of publication NEW YORK
Publisher WILEY-LISS
Language eng
Abstract Endocytosis is the process by which cells take in fluid and components of the plasma membrane. In this way cells obtain nutrients and trophic factors, retrieve membrane proteins for degradation, and sample their environment. In neuronal cells endocytosis is essential for the recycling of membrane after neurotransmitter release and plays a critical role during early developmental stages. Moreover, alterations of the endocytic pathway have been attributed a crucial role in the pathophysiology of certain neurological diseases. Although well characterized at the ultra-structural level, little is known of the dynamics and molecular organization of the neuronal endocytic pathways. In this respect most of our knowledge comes from studies of non-neuronal cells. In this review we will examine the endocytic pathways in neurons from a cell biological viewpoint by making comparisons with non-neuronal cells and in particular with another polarized cell, the epithelial cell. (C) 1993 Wiley-Liss, Inc.
Keyword Endocytosis
Neurons
Polarity
Gtp-Binding-Proteins
Anterograde Axonal-Transport
Mannose 6-Phosphate Receptor
Canine Kidney-Cells
Late Endosomes
Membranous Organelles
Retrograde Transport
Alzheimers-Disease
Amyloid Protein
Fusion Invitro
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Institute for Molecular Bioscience - Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 56 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 57 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sat, 10 Sep 2011, 06:16:40 EST by System User on behalf of Learning and Research Services (UQ Library)