The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti

Moreira, Luciano A., Ye, Yixin H., Turner, Karly, Eyles, Darryl W., McGraw, Elizabeth A. and O'Neill, Scott L. (2011) The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti. Parasites and Vectors, 4 28: 1-5. doi:10.1186/1756-3305-4-28


Author Moreira, Luciano A.
Ye, Yixin H.
Turner, Karly
Eyles, Darryl W.
McGraw, Elizabeth A.
O'Neill, Scott L.
Title The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti
Formatted title
The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti
Journal name Parasites and Vectors   Check publisher's open access policy
ISSN 1475-2883
1475-9292
1756-3305
Publication date 2011-02-28
Sub-type Article (original research)
DOI 10.1186/1756-3305-4-28
Open Access Status DOI
Volume 4
Issue 28
Start page 1
End page 5
Total pages 5
Place of publication London, U.K.
Publisher BioMed Central
Collection year 2012
Language eng
Formatted abstract
Wolbachia is an intracellular bacterium that has been stably transinfected into the mosquito vector of dengue, Aedes aegypti. This inherited infection causes a range of metabolic and phenotypic alterations in the mosquito, which might be related to neuronal abnormalities. In order to determine if these alterations were caused by the manipulation of neuroamines by this bacterium, we studied the expression of genes involved in the dopamine biosynthetic pathway and also measured the amount of dopamine in infected and uninfected mosquitoes of different ages. Wolbachia-infected mosquitoes exhibit greater expression of some genes related to the melanization pathway, but not for those directly linked to dopamine production. Although dopamine levels were higher in Wolbachia-positive mosquitoes this was not consistent across all insect ages nor was it related to the previously described Wolbachia induced "bendy" and "shaky" phenotypes.
Keyword Life-shortening wolbachia
Drosophila-melanogaster
Locomotor-activity
Mosquito
Decarboxylase
Metabolism
Gene
Infection
Receptors
Stress
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2012 Collection
School of Biological Sciences Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 06 Sep 2011, 02:25:35 EST by Gail Walter on behalf of School of Biological Sciences