In vitro biodegradation behavior of magnesium and magnesium alloy

Wang, Hao and Shi, Zhiming (2011) In vitro biodegradation behavior of magnesium and magnesium alloy. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 98B 2: 203-209. doi:10.1002/jbm.b.31769


Author Wang, Hao
Shi, Zhiming
Title In vitro biodegradation behavior of magnesium and magnesium alloy
Journal name Journal of Biomedical Materials Research Part B-Applied Biomaterials   Check publisher's open access policy
ISSN 1552-4973
1552-4981
Publication date 2011-08-01
Sub-type Article (original research)
DOI 10.1002/jbm.b.31769
Open Access Status Not yet assessed
Volume 98B
Issue 2
Start page 203
End page 209
Total pages 7
Place of publication London, United Kingdom
Publisher Academic Press
Language eng
Abstract Magnesium has the potential to be used as degradable metallic biomaterial. For magnesium and its alloys to be used as biodegradable implant materials, their degradation rates should be consistent with the rate of healing of the affected tissue, and the release of the degradation products should be within the body's acceptable absorption levels. Conventional magnesium degrades rapidly, which is undesirable. In this study, biodegradation behaviors of high purity magnesium and commercial purity magnesium alloy AZ31 in both static and dynamic Hank's solution are systematically investigated. The in vitro test results show that magnesium purification and selective alloying are effective approaches to reduce the degradation rate of magnesium. In the static condition, the corrosion products accumulate on the materials surface as a protective layer, which results in a lower degradation rate than the dynamic condition. Anodized coating can significantly further reduce the degradation rate of magnesium. This study strongly indicates that magnesium can be used as degradable implant material as long as the degradation is controlled at a low rate. Magnesium purification, selective alloying, and anodized coating are three effective approaches to reduce the rate of degradation.
Keyword Magnesium and magnesium alloy
Biodegradation
Biodegradable materials
Biodegradable implant
Biocorrosion
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mechanical & Mining Engineering Publications
Official 2012 Collection
 
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