A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

Gubbay, John, Koopman, Peter, Capel, Blanche, Economou, Androulla, Munsterberg, Andrea, Vivian, Nigel, Goodfellow, Peter and Lovell-Badge, Robin (1990) A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature, 346 6281: 245-250. doi:10.1038/346245a0


Author Gubbay, John
Koopman, Peter
Capel, Blanche
Economou, Androulla
Munsterberg, Andrea
Vivian, Nigel
Goodfellow, Peter
Lovell-Badge, Robin
Title A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes
Journal name Nature   Check publisher's open access policy
ISSN 0028-0836
1476-4687
Publication date 1990-07-01
Year available 1990
Sub-type Article (original research)
DOI 10.1038/346245a0
Open Access Status Not yet assessed
Volume 346
Issue 6281
Start page 245
End page 250
Total pages 6
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Abstract A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.
Keyword Multidisciplinary Sciences
Science & Technology - Other Topics
MULTIDISCIPLINARY SCIENCES
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID MC_U117562207
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Institute for Molecular Bioscience - Publications
 
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