A generalized transducing phage for the murine pathogen Citrobacter rodentium

Petty, Nicola K., Toribio, Ana L., Goulding, David, Foulds, Ian, Thomson, Nicholas, Dougan, Gordon and Salmond, George P. C. (2007) A generalized transducing phage for the murine pathogen Citrobacter rodentium. Microbiology, 153 9: 2984-2988. doi:10.1099/mic.0.2007/008888-0


Author Petty, Nicola K.
Toribio, Ana L.
Goulding, David
Foulds, Ian
Thomson, Nicholas
Dougan, Gordon
Salmond, George P. C.
Title A generalized transducing phage for the murine pathogen Citrobacter rodentium
Formatted title
A generalized transducing phage for the murine pathogen Citrobacter rodentium
Journal name Microbiology   Check publisher's open access policy
ISSN 1350-0872
1465-2080
Publication date 2007-09-01
Sub-type Article (original research)
DOI 10.1099/mic.0.2007/008888-0
Volume 153
Issue 9
Start page 2984
End page 2988
Total pages 5
Place of publication Reading, Berks., United Kingdom
Publisher Society for General Microbiology
Language eng
Formatted abstract
A virulent phage (φCR1) capable of generalized transduction in Citrobacter rodentium was isolated from the environment and characterized. C. rodentium is a natural pathogen of mice, causing transmissible murine colonic hyperplasia. Sequencing of its genome has recently been completed and will soon be fully annotated and published. C. rodentium is an important model organism for infections caused by the human pathogens enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC). φCR1 uses a lipopolysaccharide receptor, has a genome size of approximately 300 kb, and is able to transduce a variety of markers. φCR1 is the first reported transducing phage for C. rodentium and will be a useful tool for functional genomic analysis of this important natural murine pathogen.
© 2007 SGM.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Chemistry and Molecular Biosciences
 
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Created: Thu, 23 Jun 2011, 05:56:22 EST by Dr Nicola Petty on behalf of School of Chemistry & Molecular Biosciences