HLA antigens in tardive dyskinesia

Metzer, W. Steven, Newton, J. E. O., Steele, Russell W., Claybrook, Marsha, Paige, Stephen R., McMillan, D. E. and Hays, Sarah (1990) HLA antigens in tardive dyskinesia. Journal of Neuroimmunology, 26 2: 179-181. doi:10.1016/0165-5728(90)90089-6


Author Metzer, W. Steven
Newton, J. E. O.
Steele, Russell W.
Claybrook, Marsha
Paige, Stephen R.
McMillan, D. E.
Hays, Sarah
Title HLA antigens in tardive dyskinesia
Journal name Journal of Neuroimmunology   Check publisher's open access policy
ISSN 0165-5728
1872-8421
Publication date 1990-02-01
Sub-type Article (original research)
DOI 10.1016/0165-5728(90)90089-6
Open Access Status Not Open Access
Volume 26
Issue 2
Start page 179
End page 181
Total pages 3
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Formatted abstract
Fifty-three male, Caucasian, neuroleptic-treated patients with chronic schizophrenia were examined for the presence of tardivedyskinesia (TD) and were tissue typed. The group with TD (n = 25) was compared to the group without TD (n = 28). HLA-DR4 was more prevalent in the group with TD than in the group without TD, with a relative risk of 3.04 for TD with HLA-DR4 present, although this finding is not statistically significant when corrected for the number of nonparametric comparisons. Other investigations reported an association between HLA-B44 and TD, or between HLA-B44 and neuroleptic-induced parkinsonism. Potential explanations relating the findings of these investigations are discussed.
Keyword Tardive dyskinesia
Movement disorder
HLA antigen
Tissue antigen
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Published under Short Communication

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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