Combined use of cryotherapy and diode laser photocoagulation for the treatment threshold retinopathy of prematurity

Eustis, H.Sprague, Mungan, Nils K. and Ginsberg, Harley G. (2003) Combined use of cryotherapy and diode laser photocoagulation for the treatment threshold retinopathy of prematurity. Journal of American Association for Pediatric Ophthalmology and Strabismus, 7 2: 121-125. doi:10.1016/S1091-8531(02)42003-4


Author Eustis, H.Sprague
Mungan, Nils K.
Ginsberg, Harley G.
Title Combined use of cryotherapy and diode laser photocoagulation for the treatment threshold retinopathy of prematurity
Journal name Journal of American Association for Pediatric Ophthalmology and Strabismus   Check publisher's open access policy
ISSN 1091-8531
1528-3933
Publication date 2003-04-01
Sub-type Article (original research)
DOI 10.1016/S1091-8531(02)42003-4
Open Access Status Not Open Access
Volume 7
Issue 2
Start page 121
End page 125
Total pages 5
Place of publication Philadelphia, PA, United States
Publisher Mosby
Language eng
Formatted abstract
Purpose: Cryotherapy and indirect laser retinal photoablation are both effective in the treatment of retinopathy of prematurity (ROP). We describe the safety, efficiency, and effectiveness of combined cryotherapy and diode laser photocoagulation to treat threshold ROP.
Methods: Records of patients developing threshold ROP from January 1, 1996 through December 31, 1998, were retrospectively reviewed to identify those treated with combined cryotherapy and photocoagulation and followed up for at least 45 days postoperatively. Diode laser was used to ablate posterior avascular retina, and cryotherapy was used for anterior retina. Data reviewed included ocular and systemic complication rates, treatment duration, number of laser burns, most recent fundus examination, visual acuity, and refraction.
Results: In 13 patients, 23 eyes received combined treatment. No intraoperative complications occurred. Mean duration of anesthesia and treatment was 35 ± 8 minutes/eye. A mean of 117 ± 84 laser burns/eye were applied. In 20 of 23 eyes (87.0%), anatomic outcome was favorable at last examination. In 13 of 16 eyes (81.3%), functional (visual acuity) outcome was favorable (visual acuity better than 20/200) at 1 year. At 6 months or later, 14 of 16 eyes (87.5%) measured were myopic, of which 5 (31.3%) were highly myopic (> 6 diopters).
Conclusions: The effectiveness of treating ROP with combined cryotherapy and diode laser photocoagulation compares with that of either modality alone. By decreasing the number of laser applications, combined therapy may be faster and technically easier for eyes with very posterior ROP. This may decrease the number of complications seen when either excessive cryotherapy or laser retinal photoablation is used.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Presented as a poster at the 26th Annual Meeting of the American Association of Pediatric Ophthalmology and Strabismus, San Diego, CA, April 12-16, 2000.

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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