Selective chemical vestibulectomy: Preliminary results with human application

Amedee, R. G., Norris, C. H. and Risey, J. A. (1991). Selective chemical vestibulectomy: Preliminary results with human application. In: 1990 Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery, San Diego CA, (107-112). 9-13 September 1990. doi:10.1177/019459989110500115


Author Amedee, R. G.
Norris, C. H.
Risey, J. A.
Title of paper Selective chemical vestibulectomy: Preliminary results with human application
Conference name 1990 Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery
Conference location San Diego CA
Conference dates 9-13 September 1990
Journal name Otolaryngology - Head and Neck Surgery   Check publisher's open access policy
Place of Publication ST LOUIS
Publisher MOSBY-YEAR BOOK INC
Publication Year 1991
Year available 1991
Sub-type Fully published paper
DOI 10.1177/019459989110500115
Open Access Status Not yet assessed
ISSN 0194-5998
Volume 105
Issue 1
Start page 107
End page 112
Total pages 6
Language eng
Abstract/Summary The involved membranous labyrinth of patients with medically intractable Meniere's disease is being accessed by means of a fenestration of the bony horizontal semicircular canal in preparation for the application of a 125 or 250 mcg flake of solid streptomycin. Sensory information originating in the affected vestibular end organ is selectively blocked from reaching the central nervous system. This uniformly results in the rapid elimination of vertiginous symptoms, and at these calculated doses yields preservation of (or in some cases improvement in) preoperative cochlear thresholds. The rationale for this procedure, as detailed in earlier investigations of animals, will be briefly reviewed before highlighting our preliminary results in adult clinical trials.
Keyword MENIERES-DISEASE
LABYRINTHECTOMY
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Conference Paper
Sub-type: Fully published paper
Collection: School of Medicine Publications
 
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