Effects of the breathe right nasal strips on nasal ventilation

Gosepath, J., Mann, W. J. and Amedee, R. G. (1997) Effects of the breathe right nasal strips on nasal ventilation. American Journal of Rhinology, 11 5: 399-402. doi:10.2500/105065897781285990


Author Gosepath, J.
Mann, W. J.
Amedee, R. G.
Title Effects of the breathe right nasal strips on nasal ventilation
Journal name American Journal of Rhinology   Check publisher's open access policy
ISSN 1050-6586
Publication date 1997-09-01
Sub-type Article (original research)
DOI 10.2500/105065897781285990
Open Access Status DOI
Volume 11
Issue 5
Start page 399
End page 402
Total pages 4
Language eng
Abstract Augmented breaths, also known as sighs, constitute the normal repertoire of breathing in freely behaving humans and animals. The breaths are believed to be generated by neurones in the preBötzinger complex but under modulatory influence from higher brain centres, particularly in the limbic system due to the strong correlations between the expression of emotional behaviours such as anxiety and the occurrence of augmented breaths. The current study examines the role of the hippocampus in the motor expression of augmented breaths, and also examines the characteristics of eupneic breaths surrounding a sigh before and after stimulating the hippocampus in urethane anaesthetised Sprague-Dawley rats. Neurochemical microstimulation using the excitatory amino acid, D,L-Homocysteic acid, was used to locate areas in the hippocampus with the potential to modulated the motor expression of augmented breaths. The CA1 neurone cluster of the ventral hippocampus was found to completely suppress the expression of augmented breaths without affecting the intrinsic properties of the breaths. A similar neurone cluster, but in the dorsal field of the hippocampus, was also investigated and found to have no effects over the expression of augmented breaths. The data supports the hypothesis that there is a structural or functional relationship between neurones of the ventral hippocampus and brainstem nuclei that control augmented breaths. The implications of these findings in the context of behaviours are discussed but with due consideration of experimental conditions.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 21 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Thu, 19 May 2011, 03:20:12 EST by System User on behalf of School of Medicine